Schedule:
Please note: All rankings shown are the rankings of the teams on the date that they played one another
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2020-11-25 | Central Arkansas (143) | 0 | 0 | Ole Miss (79) | Cancelled | - | - |
| 2 | 2020-11-25 | Central Arkansas (309) | Ole Miss (105) | Cancelled | - | - | ||
| 3 | 2020-11-26 | Jackson State (329) | 0 | 0 | Ole Miss (79) | Cancelled | - | - |
| 4 | 2020-11-26 | Jackson State (301) | Ole Miss (105) | Cancelled | - | - | ||
| 5 | 2020-11-27 | Arkansas State (212) | Ole Miss (105) | Cancelled | - | - | ||
| 6 | 2020-12-04 | Memphis (136) | 0 | 0 | Ole Miss (79) | Cancelled | - | - |
| 7 | 2020-12-05 | Memphis (243) | Ole Miss (201) | Cancelled | - | - | ||
| 8 | 2020-12-10 | Jackson State (329) | 45 | 80 | Ole Miss (79) | Final | W | 35 |
| 9 | 2020-12-12 | UNC-Wilmington (90) | 58 | 78 | Ole Miss (79) | Final | W | 20 |
| 10 | 2020-12-14 | Central Arkansas (143) | 54 | 68 | Ole Miss (79) | Final | W | 14 |
| 11 | 2020-12-16 | Ole Miss (79) | 70 | 51 | Middle Tennessee (164) | Final | W | 19 |
| 12 | 2020-12-19 | Ole Miss (79) | 62 | 65 | Dayton (66) | Final | L | -3 |
| 13 | 2020-12-22 | Tennessee-Martin (205) | 43 | 90 | Ole Miss (79) | Final | W | 47 |
| 14 | 2020-12-29 | Ole Miss (79) | 64 | 82 | Alabama (15) | Final | L | -18 |
| 15 | 2021-01-02 | Wichita State (76) | 83 | 79 | Ole Miss (79) | Final | L | -4 |
| 16 | 2021-01-06 | Auburn (37) | 61 | 72 | Ole Miss (79) | Final | W | 11 |
| 17 | 2021-01-09 | South Carolina (117) | 0 | 0 | Ole Miss (87) | Cancelled | - | - |
| 18 | 2021-01-09 | LSU (77) | 75 | 61 | Ole Miss (79) | Final | L | -14 |
| 19 | 2021-01-12 | Ole Miss (79) | 63 | 72 | Florida (6) | Final | L | -9 |
| 20 | 2021-01-16 | Georgia (35) | 78 | 74 | Ole Miss (79) | Final | L | -4 |
| 21 | 2021-01-19 | Ole Miss (79) | 64 | 46 | Mississippi State (100) | Final | W | 18 |
| 22 | 2021-01-23 | Texas A&M (39) | 50 | 61 | Ole Miss (79) | Final | W | 11 |
| 23 | 2021-01-27 | Ole Miss (79) | 59 | 74 | Arkansas (16) | Final | L | -15 |
| 24 | 2021-01-30 | Ole Miss (79) | 61 | 71 | Georgia (35) | Final | L | -10 |
| 25 | 2021-02-02 | Tennessee (18) | 50 | 52 | Ole Miss (79) | Final | W | 2 |
| 26 | 2021-02-06 | Ole Miss (79) | 86 | 84 | Auburn (37) | Final/OT | W | 2 |
| 27 | 2021-02-10 | Missouri (51) | 59 | 80 | Ole Miss (79) | Final | W | 21 |
| 28 | 2021-02-13 | Ole Miss (79) | 81 | 74 | South Carolina (110) | Final | W | 7 |
| 29 | 2021-02-18 | LSU (77) | 0 | 0 | Ole Miss (79) | Cancelled | - | - |
| 30 | 2021-02-20 | Mississippi State (100) | 66 | 56 | Ole Miss (79) | Final | L | -10 |
| 31 | 2021-02-23 | Ole Miss (79) | 60 | 53 | Missouri (51) | Final | W | 7 |
| 32 | 2021-02-27 | Ole Miss (79) | 70 | 75 | Vanderbilt (17) | Final | L | -5 |
| 33 | 2021-03-02 | Kentucky (26) | 62 | 70 | Ole Miss (79) | Final | W | 8 |
| 34 | 2021-03-06 | Vanderbilt (17) | 46 | 56 | Ole Miss (79) | Final | W | 10 |
| 35 | 2021-03-11 | South Carolina (110) | 59 | 76 | Ole Miss (79) | Final | W | 17 |
| 36 | 2021-03-12 | Ole Miss (79) | 73 | 76 | LSU (77) | Final | L | -3 |
| 37 | 2021-03-19 | Louisiana Tech (70) | 70 | 61 | Ole Miss (60) | Final | L | -9 |