Schedule:
Please note: All rankings shown are the rankings of the teams on the date that they played one another
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2020-11-26 | Jackson State (329) | 0 | 0 | Ole Miss (79) | Cancelled | - | - |
| 2 | 2020-11-26 | Jackson State (301) | Ole Miss (105) | Cancelled | - | - | ||
| 3 | 2020-12-02 | Jackson State (329) | 0 | 0 | North Alabama (335) | Cancelled | - | - |
| 4 | 2020-12-02 | Jackson State (175) | North Alabama (236) | Cancelled | - | - | ||
| 5 | 2020-12-08 | Jackson State (329) | 59 | 82 | Mississippi State (100) | Final | L | -23 |
| 6 | 2020-12-10 | Jackson State (329) | 45 | 80 | Ole Miss (79) | Final | L | -35 |
| 7 | 2020-12-15 | Jackson State (329) | 58 | 85 | Louisiana Tech (185) | Final | L | -27 |
| 8 | 2020-12-17 | Jackson State (329) | 60 | 83 | Bradley (113) | Final | L | -23 |
| 9 | 2020-12-20 | Jackson State (329) | 45 | 60 | Iowa State (7) | Final | L | -15 |
| 10 | 2020-12-22 | Jackson State (329) | 0 | 0 | North Alabama (335) | Cancelled | - | - |
| 11 | 2021-01-02 | Jackson State (329) | 0 | 0 | Alabama A&M (286) | Cancelled | - | - |
| 12 | 2021-01-04 | Jackson State (329) | 60 | 44 | Alabama State (331) | Final | W | 16 |
| 13 | 2021-01-09 | Alcorn State (348) | 0 | 0 | Jackson State (329) | Cancelled | - | - |
| 14 | 2021-01-11 | Southern (259) | 0 | 0 | Jackson State (329) | Cancelled | - | - |
| 15 | 2021-01-16 | Jackson State (329) | 0 | 0 | Prairie View A&M (285) | Cancelled | - | - |
| 16 | 2021-01-18 | Jackson State (329) | 0 | 0 | Texas Southern (317) | Cancelled | - | - |
| 17 | 2021-01-23 | Jackson State (329) | 75 | 61 | Grambling (312) | Final | W | 14 |
| 18 | 2021-01-30 | Mississippi Valley State (365) | 56 | 106 | Jackson State (329) | Final | W | 50 |
| 19 | 2021-02-01 | Arkansas-Pine Bluff (303) | 55 | 63 | Jackson State (329) | Final | W | 8 |
| 20 | 2021-02-06 | Jackson State (329) | 74 | 66 | Alcorn State (348) | Final | W | 8 |
| 21 | 2021-02-08 | Jackson State (329) | 57 | 53 | Southern (259) | Final | W | 4 |
| 22 | 2021-02-13 | Prairie View A&M (285) | 0 | 0 | Jackson State (329) | Cancelled | - | - |
| 23 | 2021-02-15 | Texas Southern (192) | 0 | 0 | Jackson State (249) | Cancelled | - | - |
| 24 | 2021-02-16 | Texas Southern (317) | 0 | 0 | Jackson State (329) | Cancelled | - | - |
| 25 | 2021-02-22 | Grambling (312) | 59 | 63 | Jackson State (329) | Final | W | 4 |
| 26 | 2021-02-27 | Jackson State (329) | 68 | 54 | Mississippi Valley State (365) | Final | W | 14 |
| 27 | 2021-03-01 | Arkansas-Pine Bluff (341) | 58 | 64 | Jackson State (243) | Final (OT) | W | 6 |
| 28 | 2021-03-04 | Alabama A&M (286) | 35 | 50 | Jackson State (329) | Final | W | 15 |
| 29 | 2021-03-06 | Alabama State (331) | 54 | 79 | Jackson State (329) | Final | W | 25 |
| 30 | 2021-03-10 | Arkansas-Pine Bluff (340) | 62 | 74 | Jackson State (223) | Final | W | 12 |
| 31 | 2021-03-12 | Texas Southern (317) | 84 | 81 | Jackson State (329) | Final/OT | L | -3 |