Schedule:
Please note: All rankings shown are the rankings of the teams on the date that they played one another
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2020-11-25 | Oral Roberts (327) | 64 | 91 | Missouri (51) | Final | W | 27 |
| 2 | 2020-12-02 | Missouri (48) | Boston College (116) | Cancelled | - | - | ||
| 3 | 2020-12-02 | Missouri (51) | 83 | 75 | Oregon (102) | Final | W | 8 |
| 4 | 2020-12-06 | Missouri (51) | 72 | 62 | Wichita State (76) | Final | W | 10 |
| 5 | 2020-12-09 | Liberty (93) | 60 | 69 | Missouri (51) | Final | W | 9 |
| 6 | 2020-12-12 | Illinois (9) | 78 | 81 | Missouri (51) | Final | W | 3 |
| 7 | 2020-12-18 | Prairie View A&M (285) | 0 | 0 | Missouri (51) | Cancelled | - | - |
| 8 | 2020-12-22 | Bradley (113) | 53 | 54 | Missouri (51) | Final | W | 1 |
| 9 | 2020-12-30 | Tennessee (18) | 73 | 53 | Missouri (51) | Final | L | -20 |
| 10 | 2021-01-02 | Missouri (51) | 81 | 68 | Arkansas (16) | Final | W | 13 |
| 11 | 2021-01-05 | Missouri (51) | 63 | 78 | Mississippi State (100) | Final | L | -15 |
| 12 | 2021-01-09 | LSU (29) | 0 | 0 | Missouri (5) | Cancelled | - | - |
| 13 | 2021-01-12 | Vanderbilt (180) | 0 | 0 | Missouri (18) | Cancelled | - | - |
| 14 | 2021-01-16 | Missouri (51) | 68 | 52 | Texas A&M (39) | Final | W | 16 |
| 15 | 2021-01-19 | South Carolina (110) | 70 | 81 | Missouri (51) | Final | W | 11 |
| 16 | 2021-01-23 | Missouri (51) | 73 | 64 | Tennessee (18) | Final | W | 9 |
| 17 | 2021-01-26 | Missouri (51) | 82 | 88 | Auburn (37) | Final | L | -6 |
| 18 | 2021-01-30 | TCU (32) | 98 | 102 | Missouri (51) | Final/OT | W | 4 |
| 19 | 2021-02-03 | Kentucky (26) | 70 | 75 | Missouri (51) | Final | W | 5 |
| 20 | 2021-02-06 | Alabama (15) | 65 | 68 | Missouri (51) | Final | W | 3 |
| 21 | 2021-02-10 | Missouri (51) | 59 | 80 | Ole Miss (79) | Final | L | -21 |
| 22 | 2021-02-13 | Arkansas (16) | 86 | 81 | Missouri (51) | Final/OT | L | -5 |
| 23 | 2021-02-16 | Missouri (51) | 70 | 80 | Georgia (35) | Final | L | -10 |
| 24 | 2021-02-20 | Missouri (51) | 93 | 78 | South Carolina (110) | Final | W | 15 |
| 25 | 2021-02-23 | Ole Miss (79) | 60 | 53 | Missouri (51) | Final | L | -7 |
| 26 | 2021-02-27 | Texas A&M (39) | 0 | 0 | Missouri (51) | Cancelled | - | - |
| 27 | 2021-03-03 | Missouri (51) | 72 | 70 | Florida (6) | Final | W | 2 |
| 28 | 2021-03-06 | LSU (77) | 86 | 80 | Missouri (51) | Final | L | -6 |
| 29 | 2021-03-11 | Georgia (35) | 70 | 73 | Missouri (51) | Final | W | 3 |
| 30 | 2021-03-12 | Missouri (51) | 64 | 70 | Arkansas (16) | Final | L | -6 |
| 31 | 2021-03-20 | Missouri (34) | 68 | 72 | Oklahoma (37) | Final | L | -4 |