Schedule:
Please note: All rankings shown are the rankings of the teams on the date that they played one another
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2020-11-25 | Illinois State (94) | 67 | 94 | Ohio State (34) | Final | L | -27 |
| 2 | 2020-11-28 | Illinois State (94) | 82 | 72 | UMass-Lowell (319) | Final | W | 10 |
| 3 | 2020-12-02 | Greenville | 108 | 177 | Illinois State (94) | Final | W | 69 |
| 4 | 2020-12-05 | Illinois State (94) | 65 | 76 | Murray State (116) | Final | L | -11 |
| 5 | 2020-12-12 | Illinois State (94) | 66 | 82 | Ball State (298) | Final | L | -16 |
| 6 | 2020-12-15 | Chicago State (351) | 62 | 91 | Illinois State (94) | Final | W | 29 |
| 7 | 2020-12-27 | Illinois State (94) | 60 | 90 | Loyola-Chicago (263) | Final | L | -30 |
| 8 | 2020-12-28 | Illinois State (94) | 55 | 86 | Loyola-Chicago (263) | Final | L | -31 |
| 9 | 2020-12-30 | Illinois State (255) | Evansville (283) | Cancelled | - | - | ||
| 10 | 2021-01-01 | Valparaiso (156) | 0 | 0 | Illinois State (94) | Postponed | - | - |
| 11 | 2021-01-02 | Valparaiso (156) | 0 | 0 | Illinois State (94) | Postponed | - | - |
| 12 | 2021-01-03 | Southern Illinois (53) | Illinois State (255) | Cancelled | - | - | ||
| 13 | 2021-01-03 | Valparaiso (277) | 0 | 0 | Illinois State (255) | Cancelled | - | - |
| 14 | 2021-01-06 | Illinois State (283) | Northern Iowa (257) | Cancelled | - | - | ||
| 15 | 2021-01-09 | Indiana State (220) | Illinois State (283) | Cancelled | - | - | ||
| 16 | 2021-01-09 | Illinois State (94) | 48 | 57 | Evansville (302) | Final | L | -9 |
| 17 | 2021-01-10 | Illinois State (94) | 73 | 68 | Evansville (302) | Final | W | 5 |
| 18 | 2021-01-13 | Illinois State | Loyola-Chicago | Cancelled | - | - | ||
| 19 | 2021-01-16 | Illinois State | Bradley | Cancelled | - | - | ||
| 20 | 2021-01-16 | Indiana State (243) | 73 | 65 | Illinois State (94) | Final | L | -8 |
| 21 | 2021-01-17 | Indiana State (243) | 74 | 68 | Illinois State (94) | Final | L | -6 |
| 22 | 2021-01-20 | Valparaiso | Illinois State | Cancelled | - | - | ||
| 23 | 2021-01-20 | Bradley (113) | 56 | 71 | Illinois State (94) | Final | W | 15 |
| 24 | 2021-01-23 | Illinois State | Missouri State | Cancelled | - | - | ||
| 25 | 2021-01-23 | Valparaiso (156) | 69 | 60 | Illinois State (94) | Final | L | -9 |
| 26 | 2021-01-24 | Valparaiso (156) | 70 | 66 | Illinois State (94) | Final | L | -4 |
| 27 | 2021-01-27 | Evansville | Illinois State | Cancelled | - | - | ||
| 28 | 2021-01-31 | Bradley | Illinois State | Cancelled | - | - | ||
| 29 | 2021-01-31 | Illinois State (94) | 76 | 78 | Drake (217) | Final/OT | L | -2 |
| 30 | 2021-02-01 | Illinois State (94) | 60 | 95 | Drake (217) | Final | L | -35 |
| 31 | 2021-02-06 | Illinois State | Valparaiso | Cancelled | - | - | ||
| 32 | 2021-02-06 | Missouri State (224) | 74 | 67 | Illinois State (94) | Final | L | -7 |
| 33 | 2021-02-07 | Missouri State (224) | 72 | 62 | Illinois State (94) | Final | L | -10 |
| 34 | 2021-02-13 | Illinois State (94) | 80 | 55 | Southern Illinois (150) | Final | W | 25 |
| 35 | 2021-02-14 | Illinois State (94) | 49 | 59 | Southern Illinois (150) | Final | L | -10 |
| 36 | 2021-02-16 | Loyola-Chicago | Illinois State | Cancelled | - | - | ||
| 37 | 2021-02-18 | Illinois State (94) | 88 | 71 | Bradley (113) | Final | W | 17 |
| 38 | 2021-02-20 | Northern Iowa | Illinois State | Cancelled | - | - | ||
| 39 | 2021-02-23 | Illinois State | Indiana State | Cancelled | - | - | ||
| 40 | 2021-02-26 | Northern Iowa (89) | 70 | 56 | Illinois State (94) | Final | L | -14 |
| 41 | 2021-02-27 | Drake | Illinois State | Cancelled | - | - | ||
| 42 | 2021-02-27 | Northern Iowa (89) | 94 | 87 | Illinois State (94) | Final/2OT | L | -7 |
| 43 | 2021-03-04 | Illinois State (94) | 60 | 65 | Northern Iowa (89) | Final | L | -5 |