Schedule:
Please note: All rankings shown are the rankings of the teams on the date that they played one another
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2020-11-25 | Towson (162) | UMass-Lowell (264) | Cancelled | - | - | ||
| 2 | 2020-11-25 | San Francisco (122) | 68 | 76 | UMass-Lowell (319) | Final | W | 8 |
| 3 | 2020-11-28 | Illinois State (94) | 82 | 72 | UMass-Lowell (319) | Final | L | -10 |
| 4 | 2020-11-29 | UMass-Lowell (319) | 64 | 74 | Ohio State (34) | Final | L | -10 |
| 5 | 2020-12-03 | UMass-Lowell (319) | 59 | 90 | North Carolina State (44) | Final | L | -31 |
| 6 | 2020-12-04 | Sacred Heart (270) | 0 | 0 | UMass-Lowell (319) | Cancelled | - | - |
| 7 | 2020-12-05 | Bryant (276) | 0 | 0 | UMass-Lowell (255) | Cancelled | - | - |
| 8 | 2020-12-09 | UMass-Lowell (319) | 0 | 0 | Northeastern (300) | Cancelled | - | - |
| 9 | 2020-12-09 | UMass-Lowell (235) | Northeastern (193) | Cancelled | - | - | ||
| 10 | 2020-12-19 | Vermont (225) | 0 | 0 | UMass-Lowell (319) | Postponed | - | - |
| 11 | 2020-12-20 | Vermont (225) | 0 | 0 | UMass-Lowell (319) | Postponed | - | - |
| 12 | 2020-12-21 | Vermont (225) | 65 | 73 | UMass-Lowell (319) | Final | W | 8 |
| 13 | 2020-12-22 | Vermont (225) | 62 | 53 | UMass-Lowell (319) | Final | L | -9 |
| 14 | 2020-12-27 | UMass-Lowell (319) | 58 | 73 | Stony Brook (213) | Final | L | -15 |
| 15 | 2020-12-28 | UMass-Lowell (319) | 64 | 71 | Stony Brook (213) | Final | L | -7 |
| 16 | 2021-01-02 | NJIT (306) | 73 | 67 | UMass-Lowell (319) | Final | L | -6 |
| 17 | 2021-01-03 | NJIT (306) | 60 | 74 | UMass-Lowell (319) | Final | W | 14 |
| 18 | 2021-01-09 | Hartford | 62 | 71 | UMass-Lowell (319) | Final | W | 9 |
| 19 | 2021-01-10 | Hartford | 75 | 58 | UMass-Lowell (319) | Final | L | -17 |
| 20 | 2021-01-16 | UMass-Lowell (319) | 92 | 78 | Binghamton (359) | Final | W | 14 |
| 21 | 2021-01-17 | UMass-Lowell (319) | 77 | 67 | Binghamton (359) | Final | W | 10 |
| 22 | 2021-01-23 | UMBC (134) | 0 | 0 | UMass-Lowell (245) | Cancelled | - | - |
| 23 | 2021-01-24 | UMBC (128) | 0 | 0 | UMass-Lowell (240) | Cancelled | - | - |
| 24 | 2021-01-30 | UMass-Lowell (319) | 0 | 0 | Albany (330) | Postponed | - | - |
| 25 | 2021-01-31 | UMass-Lowell (319) | 0 | 0 | Albany (330) | Postponed | - | - |
| 26 | 2021-02-05 | UMass-Lowell (319) | 74 | 69 | New Hampshire (346) | Final | W | 5 |
| 27 | 2021-02-06 | Maine | 0 | 0 | UMass-Lowell | Cancelled | - | - |
| 28 | 2021-02-06 | UMass-Lowell (319) | 63 | 74 | New Hampshire (346) | Final | L | -11 |
| 29 | 2021-02-07 | Maine | 0 | 0 | UMass-Lowell | Cancelled | - | - |
| 30 | 2021-02-12 | UMass-Lowell (319) | 79 | 71 | Albany (330) | Final | W | 8 |
| 31 | 2021-02-13 | UMass-Lowell (319) | 69 | 81 | Albany (330) | Final | L | -12 |
| 32 | 2021-02-20 | New Hampshire (346) | 69 | 67 | UMass-Lowell (319) | Final | L | -2 |
| 33 | 2021-02-27 | UMass-Lowell | 0 | 0 | UMBC | Cancelled | - | - |
| 34 | 2021-02-27 | Stony Brook (213) | 62 | 64 | UMass-Lowell (319) | Final | W | 2 |
| 35 | 2021-02-28 | UMass-Lowell | 0 | 0 | UMBC | Cancelled | - | - |
| 36 | 2021-02-28 | UMass-Lowell (319) | 72 | 64 | New Hampshire (346) | Final | W | 8 |
| 37 | 2021-03-06 | UMass-Lowell (319) | 79 | 77 | UMBC (198) | Final | W | 2 |
| 38 | 2021-03-13 | UMass-Lowell (207) | 50 | 64 | Hartford (168) | Final | L | -14 |