NCAA Women's Basketball Schedule:
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2021-11-09 | Illinois State (82) | 60 | 77 | Northern Illinois (143) | Final | W | 17 |
| 2 | 2021-11-14 | Northern Illinois (143) | 53 | 70 | Harvard | Final | L | -17 |
| 3 | 2021-11-22 | Bradley (121) | 59 | 80 | Northern Illinois (204) | Final | W | 21 |
| 4 | 2021-11-28 | Milwaukee (230) | 50 | 69 | Northern Illinois (141) | Final | W | 19 |
| 5 | 2021-12-03 | Northern Illinois (119) | 83 | 92 | Western Illinois (141) | Final/OT | L | -9 |
| 6 | 2021-12-04 | Eastern Illinois (329) | 87 | 81 | Northern Illinois (310) | Final | L | -6 |
| 7 | 2021-12-12 | Northern Illinois (191) | 44 | 96 | Drake (70) | Final | L | -52 |
| 8 | 2021-12-16 | Northern Illinois (223) | 71 | 103 | DePaul (34) | Final | L | -32 |
| 9 | 2021-12-21 | Colorado State (67) | 0 | 0 | Northern Illinois (220) | Cancelled | - | - |
| 10 | 2021-12-29 | Akron (249) | 0 | 0 | Northern Illinois (215) | Postponed | - | - |
| 11 | 2022-01-01 | Northern Illinois (215) | 68 | 72 | Central Michigan (289) | Final | L | -4 |
| 12 | 2022-01-05 | Ball State (69) | 83 | 82 | Northern Illinois (310) | Final/OT | L | -1 |
| 13 | 2022-01-08 | Northern Illinois (310) | 71 | 68 | Ohio (163) | Final | W | 3 |
| 14 | 2022-01-12 | Northern Illinois (310) | 0 | 0 | Western Michigan (281) | Postponed | - | - |
| 15 | 2022-01-15 | Toledo (74) | 73 | 52 | Northern Illinois (234) | Final | L | -21 |
| 16 | 2022-01-19 | Northern Illinois (310) | 56 | 61 | Miami (OH) (74) | Final | L | -5 |
| 17 | 2022-01-22 | Northern Illinois (252) | 85 | 76 | Eastern Michigan (238) | Final | W | 9 |
| 18 | 2022-01-24 | Akron (131) | 67 | 79 | Northern Illinois (252) | Final | W | 12 |
| 19 | 2022-01-26 | Kent State (102) | 55 | 61 | Northern Illinois (215) | Final | W | 6 |
| 20 | 2022-01-29 | Northern Illinois (215) | 61 | 68 | Buffalo (64) | Final | L | -7 |
| 21 | 2022-01-31 | Northern Illinois (310) | 61 | 47 | Western Michigan (281) | Final | W | 14 |
| 22 | 2022-02-02 | Bowling Green (139) | 64 | 54 | Northern Illinois (178) | Final | L | -10 |
| 23 | 2022-02-06 | Ohio (103) | 70 | 80 | Northern Illinois (178) | Final | W | 10 |
| 24 | 2022-02-09 | Northern Illinois (310) | 52 | 81 | Bowling Green (188) | Final | L | -29 |
| 25 | 2022-02-12 | Buffalo (75) | 64 | 69 | Northern Illinois (178) | Final/OT | W | 5 |
| 26 | 2022-02-16 | Northern Illinois (310) | 43 | 67 | Kent State (173) | Final | L | -24 |
| 27 | 2022-02-19 | Western Michigan (144) | 55 | 73 | Northern Illinois (180) | Final | W | 18 |
| 28 | 2022-02-23 | Eastern Michigan (249) | 65 | 72 | Northern Illinois (176) | Final | W | 7 |
| 29 | 2022-02-26 | Northern Illinois (176) | 77 | 72 | Ball State (114) | Final | W | 5 |
| 30 | 2022-03-02 | Northern Illinois (166) | 56 | 74 | Toledo (56) | Final | L | -18 |
| 31 | 2022-03-05 | Central Michigan (294) | 49 | 69 | Northern Illinois (166) | Final | W | 20 |
| 32 | 2022-03-09 | Ball State (110) | 60 | 54 | Northern Illinois (170) | Final | L | -6 |