Schedule:
| Game | Date | Away Team (Rank) | Away Score | Home Team (Rank) | Home Score | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2022-09-03 | Indiana Wesleyan | 17 | Valparaiso (237) | 20 | Final | W | 3 |
| 2 | 2022-09-10 | Valparaiso (237) | 21 | Illinois State (184) | 28 | Final | L | -7 |
| 3 | 2022-09-17 | Valparaiso (245) | 13 | Dartmouth (168) | 35 | Final | L | -22 |
| 4 | 2022-09-24 | San Diego (253) | 21 | Valparaiso (233) | 28 | Final | W | 7 |
| 5 | 2022-10-08 | Valparaiso (221) | 41 | Presbyterian (258) | 21 | Final | W | 20 |
| 6 | 2022-10-15 | Butler (200) | 26 | Valparaiso (225) | 25 | Final | L | -1 |
| 7 | 2022-10-22 | Valparaiso (224) | 40 | Morehead State (251) | 35 | Final | W | 5 |
| 8 | 2022-10-29 | Valparaiso (232) | 24 | Dayton (204) | 31 | Final | L | -7 |
| 9 | 2022-11-05 | St. Thomas (179) | 34 | Valparaiso (236) | 7 | Final | L | -27 |
| 10 | 2022-11-12 | Valparaiso (233) | 45 | Marist (244) | 24 | Final | W | 21 |
| 11 | 2022-11-19 | Drake (249) | 24 | Valparaiso (241) | 0 | Final | L | -24 |
| 12 | 2022-12-03 | Valparaiso (244) | 3 | New Mexico State (125) | 65 | Final | L | -62 |