Schedule:
| Game | Date | Away Team (Rank) | Away Score | Home Team (Rank) | Home Score | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2016-09-03 | LSU (10) | 14 | Wisconsin (20) | 16 | Final | L | -2 |
| 2 | 2016-09-10 | Jacksonville State | 13 | LSU | 34 | Final | W | 21 |
| 3 | 2016-09-17 | Mississippi State | 20 | LSU | 23 | Final | W | 3 |
| 4 | 2016-09-24 | LSU (45) | 13 | Auburn (70) | 18 | Final | L | -5 |
| 5 | 2016-10-01 | Missouri (44) | 7 | LSU (65) | 42 | Final | W | 35 |
| 6 | 2016-10-08 | LSU (49) | 0 | Florida (19) | 0 | Postponed | - | - |
| 7 | 2016-10-15 | Southern Miss (63) | 10 | LSU (51) | 45 | Final | W | 35 |
| 8 | 2016-10-22 | Ole Miss (35) | 21 | LSU (34) | 38 | Final | W | 17 |
| 9 | 2016-11-05 | Alabama (1) | 10 | LSU (22) | 0 | Final | L | -10 |
| 10 | 2016-11-12 | LSU (24) | 38 | Arkansas (27) | 10 | Final | W | 28 |
| 11 | 2016-11-18 | South Alabama (95) | 0 | LSU (20) | 0 | 11/19 - TBD | - | - |
| 12 | 2016-11-19 | Florida (23) | 16 | LSU (20) | 10 | Final | L | -6 |
| 13 | 2016-11-24 | LSU (25) | 54 | Texas A&M (19) | 39 | Final | W | 15 |
| 14 | 2016-12-31 | LSU (16) | 29 | Louisville (12) | 9 | Final | W | 20 |