Schedule:
| Game | Date | Away Team (Rank) | Away Score | Home Team (Rank) | Home Score | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2022-09-01 | Limestone | 21 | Gardner-Webb (203) | 56 | Final | W | 35 |
| 2 | 2022-09-10 | Gardner-Webb (203) | 27 | Coastal Carolina (38) | 31 | Final | L | -4 |
| 3 | 2022-09-17 | Gardner-Webb (204) | 24 | Elon (151) | 30 | Final | L | -6 |
| 4 | 2022-09-24 | Mercer (148) | 45 | Gardner-Webb (215) | 14 | Final | L | -31 |
| 5 | 2022-10-01 | Gardner-Webb (206) | 7 | Marshall (77) | 28 | Final | L | -21 |
| 6 | 2022-10-08 | Gardner-Webb (191) | 48 | Robert Morris (256) | 0 | Final | W | 48 |
| 7 | 2022-10-15 | Gardner-Webb (190) | 20 | Liberty (32) | 21 | Final | L | -1 |
| 8 | 2022-10-22 | Gardner-Webb (182) | 28 | Charleston Southern (233) | 14 | Final | W | 14 |
| 9 | 2022-10-29 | Bryant (231) | 40 | Gardner-Webb (182) | 48 | Final | W | 8 |
| 10 | 2022-11-12 | Gardner-Webb (173) | 42 | Campbell (188) | 35 | Final | W | 7 |
| 11 | 2022-11-19 | North Carolina A&T (182) | 17 | Gardner-Webb (163) | 38 | Final | W | 21 |
| 12 | 2022-11-26 | Gardner-Webb (159) | 52 | Eastern Kentucky (162) | 41 | Final | W | 11 |
| 13 | 2022-12-03 | Gardner-Webb (161) | 14 | William & Mary (90) | 54 | Final | L | -40 |