Schedule:
| Game | Date | Away Team (Rank) | Away Score | Home Team (Rank) | Home Score | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2022-09-03 | Western Carolina (201) | 52 | Charleston Southern (199) | 38 | Final | L | -14 |
| 2 | 2022-09-10 | Charleston Southern (199) | 3 | North Carolina State (27) | 55 | Final | L | -52 |
| 3 | 2022-09-17 | Charleston Southern (235) | 17 | Eastern Kentucky (132) | 40 | Final | L | -23 |
| 4 | 2022-09-24 | Furman (162) | 24 | Charleston Southern (245) | 19 | Final | L | -5 |
| 5 | 2022-10-08 | Charleston Southern (240) | 28 | Campbell (156) | 34 | Final | L | -6 |
| 6 | 2022-10-15 | Charleston Southern (224) | 24 | Bryant (229) | 23 | Final | W | 1 |
| 7 | 2022-10-22 | Gardner-Webb (182) | 28 | Charleston Southern (233) | 14 | Final | L | -14 |
| 8 | 2022-10-29 | Charleston Southern (236) | 20 | Kennesaw State (198) | 30 | Final | L | -10 |
| 9 | 2022-11-05 | Robert Morris (258) | 21 | Charleston Southern (231) | 34 | Final | W | 13 |
| 10 | 2022-11-12 | Charleston Southern (235) | 10 | North Carolina A&T (174) | 20 | Final | L | -10 |