Schedule:
Please note: All rankings shown are the rankings of the teams on the date that they played one another
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2015-11-13 | UMBC (344) | 73 | 78 | Wake Forest (117) | Final | W | 5 |
| 2 | 2015-11-15 | Wake Forest (117) | 90 | 82 | Bucknell (176) | Final | W | 8 |
| 3 | 2015-11-18 | Richmond (72) | 91 | 82 | Wake Forest (117) | Final | L | -9 |
| 4 | 2015-11-23 | Wake Forest (117) | 82 | 78 | Indiana (38) | Final | W | 4 |
| 5 | 2015-11-24 | Vanderbilt (62) | 86 | 64 | Wake Forest (117) | Final | L | -22 |
| 6 | 2015-11-25 | Wake Forest (117) | 80 | 77 | UCLA (47) | Final | W | 3 |
| 7 | 2015-11-30 | Wake Forest (117) | 69 | 68 | Rutgers (161) | Final | W | 1 |
| 8 | 2015-12-04 | Arkansas (22) | 85 | 88 | Wake Forest (117) | Final | W | 3 |
| 9 | 2015-12-15 | UNC-Greensboro (291) | 71 | 81 | Wake Forest (70) | Final | W | 10 |
| 10 | 2015-12-18 | Coastal Carolina (175) | 77 | 83 | Wake Forest (70) | Final | W | 6 |
| 11 | 2015-12-22 | Xavier (2) | 78 | 70 | Wake Forest (66) | Final | L | -8 |
| 12 | 2015-12-29 | Wake Forest (69) | 77 | 71 | LSU (105) | Final | W | 6 |
| 13 | 2016-01-03 | Wake Forest (69) | 57 | 65 | Louisville (11) | Final | L | -8 |
| 14 | 2016-01-06 | Duke (18) | 91 | 75 | Wake Forest (68) | Final | L | -16 |
| 15 | 2016-01-10 | North Carolina State (75) | 74 | 77 | Wake Forest (68) | Final | W | 3 |
| 16 | 2016-01-13 | Wake Forest (69) | 91 | 93 | Virginia Tech (85) | Final | L | -2 |
| 17 | 2016-01-16 | Syracuse (84) | 83 | 55 | Wake Forest (69) | Final | L | -28 |
| 18 | 2016-01-20 | Wake Forest (90) | 68 | 83 | North Carolina (7) | Final | L | -15 |
| 19 | 2016-01-23 | Wake Forest (90) | 63 | 77 | Miami (15) | Final | L | -14 |
| 20 | 2016-01-26 | Virginia (16) | 72 | 71 | Wake Forest (95) | Final | L | -1 |
| 21 | 2016-01-31 | Wake Forest (95) | 62 | 85 | Notre Dame (32) | Final | L | -23 |
| 22 | 2016-02-02 | Clemson (54) | 76 | 62 | Wake Forest (101) | Final | L | -14 |
| 23 | 2016-02-06 | Florida State (43) | 91 | 71 | Wake Forest (101) | Final | L | -20 |
| 24 | 2016-02-10 | Wake Forest (106) | 66 | 71 | Georgia Tech (67) | Final | L | -5 |
| 25 | 2016-02-13 | Wake Forest (106) | 88 | 99 | North Carolina State (89) | Final | L | -11 |
| 26 | 2016-02-16 | Wake Forest (112) | 96 | 101 | Pittsburgh (30) | Final/2OT | L | -5 |
| 27 | 2016-02-21 | Boston College (206) | 48 | 74 | Wake Forest (112) | Final | W | 26 |
| 28 | 2016-02-24 | Notre Dame (28) | 69 | 58 | Wake Forest (114) | Final | L | -11 |
| 29 | 2016-02-28 | Virginia Tech (86) | 81 | 74 | Wake Forest (114) | Final | L | -7 |
| 30 | 2016-03-01 | Wake Forest (116) | 71 | 79 | Duke (12) | Final | L | -8 |
| 31 | 2016-03-08 | Wake Forest (119) | 72 | 75 | North Carolina State (90) | Final | L | -3 |