Schedule:
Please note: All rankings shown are the rankings of the teams on the date that they played one another
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2015-11-13 | St. Francis (PA) (221) | 56 | 87 | Notre Dame (8) | Final | W | 31 |
| 2 | 2015-11-17 | Milwaukee (222) | 78 | 86 | Notre Dame (8) | Final | W | 8 |
| 3 | 2015-11-21 | UMass-Lowell (290) | 57 | 83 | Notre Dame (8) | Final | W | 26 |
| 4 | 2015-11-26 | Notre Dame (8) | 68 | 70 | Monmouth (182) | Final | L | -2 |
| 5 | 2015-11-27 | Notre Dame (8) | 68 | 62 | Iowa (29) | Final | W | 6 |
| 6 | 2015-11-29 | Alabama (68) | 74 | 73 | Notre Dame (8) | Final | L | -1 |
| 7 | 2015-12-02 | Notre Dame (8) | 84 | 79 | Illinois (46) | Final | W | 5 |
| 8 | 2015-12-08 | Stony Brook (100) | 61 | 86 | Notre Dame (57) | Final | W | 25 |
| 9 | 2015-12-13 | Loyola-Chicago (161) | 61 | 81 | Notre Dame (57) | Final | W | 20 |
| 10 | 2015-12-19 | Notre Dame (33) | 73 | 80 | Indiana (35) | Final | L | -7 |
| 11 | 2015-12-21 | Youngstown State (254) | 78 | 87 | Notre Dame (33) | Final | W | 9 |
| 12 | 2015-12-29 | Liberty (345) | 56 | 73 | Notre Dame (46) | Final | W | 17 |
| 13 | 2016-01-02 | Notre Dame (46) | 66 | 77 | Virginia (8) | Final | L | -11 |
| 14 | 2016-01-07 | Notre Dame (52) | 82 | 54 | Boston College (175) | Final | W | 28 |
| 15 | 2016-01-09 | Pittsburgh (14) | 86 | 82 | Notre Dame (52) | Final | L | -4 |
| 16 | 2016-01-13 | Georgia Tech (47) | 64 | 72 | Notre Dame (50) | Final | W | 8 |
| 17 | 2016-01-16 | Notre Dame (50) | 95 | 91 | Duke (11) | Final | W | 4 |
| 18 | 2016-01-20 | Virginia Tech (71) | 81 | 83 | Notre Dame (34) | Final | W | 2 |
| 19 | 2016-01-23 | Boston College (194) | 49 | 76 | Notre Dame (34) | Final | W | 27 |
| 20 | 2016-01-28 | Notre Dame (32) | 66 | 81 | Syracuse (56) | Final | L | -15 |
| 21 | 2016-01-31 | Wake Forest (95) | 62 | 85 | Notre Dame (32) | Final | W | 23 |
| 22 | 2016-02-03 | Notre Dame (37) | 70 | 79 | Miami (16) | Final | L | -9 |
| 23 | 2016-02-06 | North Carolina (4) | 76 | 80 | Notre Dame (37) | Final | W | 4 |
| 24 | 2016-02-08 | Notre Dame (37) | 89 | 83 | Clemson (54) | Final | W | 6 |
| 25 | 2016-02-13 | Louisville (11) | 66 | 71 | Notre Dame (31) | Final | W | 5 |
| 26 | 2016-02-20 | Notre Dame (22) | 62 | 63 | Georgia Tech (75) | Final | L | -1 |
| 27 | 2016-02-24 | Notre Dame (28) | 69 | 58 | Wake Forest (114) | Final | W | 11 |
| 28 | 2016-02-27 | Notre Dame (28) | 56 | 77 | Florida State (56) | Final | L | -21 |
| 29 | 2016-03-02 | Miami (6) | 68 | 50 | Notre Dame (32) | Final | L | -18 |
| 30 | 2016-03-05 | North Carolina State (81) | 75 | 89 | Notre Dame (32) | Final | W | 14 |
| 31 | 2016-03-10 | Duke (16) | 79 | 84 | Notre Dame (32) | Final/OT | W | 5 |
| 32 | 2016-03-11 | Notre Dame (32) | 47 | 78 | North Carolina (8) | Final | L | -31 |
| 33 | 2016-03-18 | Michigan (41) | 63 | 70 | Notre Dame (33) | Final - 0:00 | W | 7 |
| 34 | 2016-03-20 | Stephen F. Austin (69) | 75 | 76 | Notre Dame (33) | Final - 0:00 | W | 1 |
| 35 | 2016-03-25 | Wisconsin (43) | 56 | 61 | Notre Dame (33) | Final - 0:00 | W | 5 |
| 36 | 2016-03-27 | Notre Dame (33) | 74 | 88 | North Carolina (4) | Final - 0:00 | L | -14 |