Schedule:
Please note: All rankings shown are the rankings of the teams on the date that they played one another
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2015-11-13 | Pittsburgh (65) | 37 | 35 | Gonzaga (7) | Canceled | W | 2 |
| 2 | 2015-11-17 | St. Joseph's (IN) | 43 | 84 | Pittsburgh (65) | Final | W | 41 |
| 3 | 2015-11-20 | Detroit (199) | 79 | 95 | Pittsburgh (65) | Final | W | 16 |
| 4 | 2015-11-25 | Cornell (213) | 49 | 93 | Pittsburgh (65) | Final | W | 44 |
| 5 | 2015-11-28 | Kent State (116) | 76 | 85 | Pittsburgh (65) | Final | W | 9 |
| 6 | 2015-12-01 | Purdue (36) | 72 | 59 | Pittsburgh (65) | Final | L | -13 |
| 7 | 2015-12-04 | Pittsburgh (65) | 96 | 75 | Duquesne (210) | Final | W | 21 |
| 8 | 2015-12-06 | Central Arkansas (349) | 47 | 100 | Pittsburgh (65) | Final | W | 53 |
| 9 | 2015-12-11 | Eastern Washington (206) | 51 | 84 | Pittsburgh (13) | Final | W | 33 |
| 10 | 2015-12-13 | Morehead State (163) | 62 | 72 | Pittsburgh (13) | Final | W | 10 |
| 11 | 2015-12-20 | Pittsburgh (8) | 94 | 69 | Davidson (44) | Final | W | 25 |
| 12 | 2015-12-23 | Western Carolina (209) | 73 | 79 | Pittsburgh (7) | Final | W | 6 |
| 13 | 2015-12-30 | Syracuse (70) | 61 | 72 | Pittsburgh (10) | Final | W | 11 |
| 14 | 2016-01-02 | Maryland-Eastern Shore (325) | 58 | 92 | Pittsburgh (10) | Final | W | 34 |
| 15 | 2016-01-06 | Georgia Tech (59) | 84 | 89 | Pittsburgh (14) | Final | W | 5 |
| 16 | 2016-01-09 | Pittsburgh (14) | 86 | 82 | Notre Dame (52) | Final | W | 4 |
| 17 | 2016-01-14 | Pittsburgh (10) | 41 | 59 | Louisville (17) | Final | L | -18 |
| 18 | 2016-01-16 | Boston College (183) | 61 | 84 | Pittsburgh (10) | Final | W | 23 |
| 19 | 2016-01-19 | North Carolina State (96) | 78 | 61 | Pittsburgh (12) | Final | L | -17 |
| 20 | 2016-01-23 | Pittsburgh (12) | 74 | 72 | Florida State (47) | Final | W | 2 |
| 21 | 2016-01-27 | Pittsburgh (18) | 60 | 73 | Clemson (65) | Final | L | -13 |
| 22 | 2016-01-31 | Virginia Tech (78) | 71 | 90 | Pittsburgh (18) | Final | W | 19 |
| 23 | 2016-02-06 | Virginia (12) | 64 | 50 | Pittsburgh (20) | Final | L | -14 |
| 24 | 2016-02-09 | Pittsburgh (24) | 63 | 65 | Miami (13) | Final | L | -2 |
| 25 | 2016-02-14 | Pittsburgh (24) | 64 | 85 | North Carolina (10) | Final | L | -21 |
| 26 | 2016-02-16 | Wake Forest (112) | 96 | 101 | Pittsburgh (30) | Final/2OT | W | 5 |
| 27 | 2016-02-20 | Pittsburgh (30) | 66 | 52 | Syracuse (38) | Final | W | 14 |
| 28 | 2016-02-24 | Louisville (9) | 67 | 60 | Pittsburgh (25) | Final | L | -7 |
| 29 | 2016-02-28 | Duke (11) | 62 | 76 | Pittsburgh (25) | Final | W | 14 |
| 30 | 2016-03-02 | Pittsburgh (26) | 61 | 65 | Virginia Tech (77) | Final | L | -4 |
| 31 | 2016-03-05 | Pittsburgh (26) | 59 | 63 | Georgia Tech (57) | Final | L | -4 |
| 32 | 2016-03-09 | Syracuse (46) | 71 | 72 | Pittsburgh (30) | Final | W | 1 |
| 33 | 2016-03-10 | Pittsburgh (30) | 71 | 88 | North Carolina (8) | Final | L | -17 |
| 34 | 2016-03-18 | Pittsburgh (31) | 43 | 47 | Wisconsin (43) | Final - 0:00 | L | -4 |