Schedule:
Please note: All rankings shown are the rankings of the teams on the date that they played one another
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2015-11-13 | Miami (OH) (216) | 72 | 81 | Xavier (30) | Final | W | 9 |
| 2 | 2015-11-17 | Missouri (180) | 66 | 78 | Xavier (30) | Final | W | 12 |
| 3 | 2015-11-20 | Xavier (30) | 86 | 70 | Michigan (66) | Final | W | 16 |
| 4 | 2015-11-23 | Northern Kentucky (250) | 66 | 78 | Xavier (30) | Final | W | 12 |
| 5 | 2015-11-26 | Alabama (68) | 45 | 64 | Xavier (30) | Final | W | 19 |
| 6 | 2015-11-27 | Xavier (30) | 87 | 77 | USC (150) | Final | W | 10 |
| 7 | 2015-11-29 | Xavier (30) | 90 | 61 | Dayton (41) | Final | W | 29 |
| 8 | 2015-12-05 | Western Kentucky (127) | 64 | 95 | Xavier (30) | Final | W | 31 |
| 9 | 2015-12-08 | Wright State (293) | 55 | 90 | Xavier (3) | Final | W | 35 |
| 10 | 2015-12-12 | Cincinnati (12) | 55 | 65 | Xavier (3) | Final | W | 10 |
| 11 | 2015-12-19 | Auburn (89) | 61 | 85 | Xavier (2) | Final | W | 24 |
| 12 | 2015-12-22 | Xavier (2) | 78 | 70 | Wake Forest (66) | Final | W | 8 |
| 13 | 2015-12-31 | Xavier (2) | 64 | 95 | Villanova (15) | Final | L | -31 |
| 14 | 2016-01-02 | Butler (9) | 69 | 88 | Xavier (2) | Final | W | 19 |
| 15 | 2016-01-06 | Xavier (3) | 74 | 66 | St. John's (200) | Final | W | 8 |
| 16 | 2016-01-12 | DePaul (171) | 64 | 84 | Xavier (6) | Final | W | 20 |
| 17 | 2016-01-16 | Xavier (6) | 74 | 66 | Marquette (68) | Final | W | 8 |
| 18 | 2016-01-19 | Georgetown (80) | 81 | 72 | Xavier (3) | Final | L | -9 |
| 19 | 2016-01-23 | Seton Hall (43) | 76 | 84 | Xavier (3) | Final | W | 8 |
| 20 | 2016-01-26 | Xavier (3) | 75 | 68 | Providence (21) | Final | W | 7 |
| 21 | 2016-01-30 | Xavier (3) | 86 | 65 | DePaul (157) | Final | W | 21 |
| 22 | 2016-02-03 | St. John's (207) | 83 | 90 | Xavier (2) | Final | W | 7 |
| 23 | 2016-02-06 | Marquette (62) | 82 | 90 | Xavier (2) | Final | W | 8 |
| 24 | 2016-02-09 | Xavier (2) | 56 | 70 | Creighton (61) | Final | L | -14 |
| 25 | 2016-02-13 | Xavier (2) | 74 | 57 | Butler (35) | Final | W | 17 |
| 26 | 2016-02-17 | Providence (36) | 74 | 85 | Xavier (4) | Final | W | 11 |
| 27 | 2016-02-20 | Xavier (4) | 88 | 70 | Georgetown (72) | Final | W | 18 |
| 28 | 2016-02-24 | Villanova (1) | 83 | 90 | Xavier (3) | Final | W | 7 |
| 29 | 2016-02-28 | Xavier (3) | 81 | 90 | Seton Hall (35) | Final | L | -9 |
| 30 | 2016-03-05 | Creighton (52) | 93 | 98 | Xavier (3) | Final | W | 5 |
| 31 | 2016-03-10 | Marquette (69) | 72 | 90 | Xavier (4) | Final | W | 18 |
| 32 | 2016-03-11 | Seton Hall (27) | 87 | 83 | Xavier (4) | Final | L | -4 |
| 33 | 2016-03-18 | Weber State (126) | 53 | 71 | Xavier (7) | Final - 0:00 | W | 18 |
| 34 | 2016-03-20 | Wisconsin (43) | 66 | 63 | Xavier (7) | Final - 0:00 | L | -3 |