Schedule:
Please note: All rankings shown are the rankings of the teams on the date that they played one another
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2020-11-27 | Rice (228) | 68 | 53 | Incarnate Word (280) | Final | W | 15 |
| 2 | 2020-11-28 | Lady of the Lake | 64 | 103 | Rice (228) | Final | W | 39 |
| 3 | 2020-12-03 | LeTourneau | 74 | 94 | Rice (228) | Final | W | 20 |
| 4 | 2020-12-05 | Rice (228) | 86 | 64 | Houston Christian (305) | Final | W | 22 |
| 5 | 2020-12-05 | Rice (60) | 86 | 64 | Houston Baptist (336) | Final | W | 22 |
| 6 | 2020-12-12 | Rice (228) | 0 | 0 | Houston (5) | Cancelled | - | - |
| 7 | 2020-12-13 | New Mexico (49) | 72 | 61 | Rice (228) | Final | L | -11 |
| 8 | 2020-12-15 | Houston Baptist (323) | 79 | 90 | Rice (149) | Final | W | 11 |
| 9 | 2020-12-19 | Rice (228) | 69 | 82 | Sam Houston State (120) | Final | L | -13 |
| 10 | 2020-12-21 | Incarnate Word (339) | 0 | 0 | Rice (149) | Cancelled | - | - |
| 11 | 2020-12-21 | New Orleans (236) | 62 | 73 | Rice (228) | Final | W | 11 |
| 12 | 2021-01-01 | UTSA (344) | 86 | 95 | Rice (228) | Final | W | 9 |
| 13 | 2021-01-02 | UTSA (344) | 69 | 84 | Rice (228) | Final | W | 15 |
| 14 | 2021-01-08 | Rice (228) | 89 | 101 | UTEP (274) | Final | L | -12 |
| 15 | 2021-01-09 | Rice (228) | 71 | 68 | UTEP (274) | Final | W | 3 |
| 16 | 2021-01-15 | Old Dominion (254) | 59 | 69 | Rice (228) | Final | W | 10 |
| 17 | 2021-01-16 | Old Dominion (254) | 61 | 58 | Rice (228) | Final | L | -3 |
| 18 | 2021-01-22 | Rice (228) | 68 | 78 | UAB (115) | Final | L | -10 |
| 19 | 2021-01-23 | Rice (228) | 74 | 86 | UAB (115) | Final | L | -12 |
| 20 | 2021-01-28 | North Texas (125) | 0 | 0 | Rice (228) | Postponed | - | - |
| 21 | 2021-01-29 | North Texas (125) | 79 | 74 | Rice (228) | Final | L | -5 |
| 22 | 2021-01-30 | Rice (228) | 0 | 0 | North Texas (125) | Postponed | - | - |
| 23 | 2021-01-31 | Rice (228) | 53 | 79 | North Texas (125) | Final | L | -26 |
| 24 | 2021-02-05 | Southern Miss (201) | 62 | 88 | Rice (228) | Final | W | 26 |
| 25 | 2021-02-06 | Southern Miss (201) | 68 | 76 | Rice (228) | Final | W | 8 |
| 26 | 2021-02-12 | Rice (228) | 71 | 77 | Western Kentucky (154) | Final | L | -6 |
| 27 | 2021-02-13 | Rice (228) | 66 | 89 | Western Kentucky (154) | Final | L | -23 |
| 28 | 2021-02-19 | Marshall (155) | 0 | 0 | Rice (228) | Cancelled | - | - |
| 29 | 2021-02-20 | Marshall (155) | 0 | 0 | Rice (228) | Cancelled | - | - |
| 30 | 2021-02-21 | Marshall (155) | 0 | 0 | Rice (228) | Cancelled | - | - |
| 31 | 2021-02-26 | Rice (228) | 57 | 101 | Louisiana Tech (185) | Final | L | -44 |
| 32 | 2021-02-27 | Rice (228) | 58 | 79 | Louisiana Tech (185) | Final | L | -21 |
| 33 | 2021-03-05 | Lady of the Lake | 77 | 80 | Rice (228) | Final | W | 3 |
| 34 | 2021-03-09 | Southern Miss (201) | 52 | 61 | Rice (228) | Final | W | 9 |
| 35 | 2021-03-10 | Rice (204) | 72 | 68 | Marshall (77) | Final | W | 4 |
| 36 | 2021-03-11 | Rice (228) | 60 | 73 | UAB (115) | Final | L | -13 |