Schedule:
Please note: All rankings shown are the rankings of the teams on the date that they played one another
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2020-12-02 | Houston Christian (305) | 75 | 102 | SMU (45) | Final | L | -27 |
| 2 | 2020-12-05 | Rice (228) | 86 | 64 | Houston Christian (305) | Final | L | -22 |
| 3 | 2020-12-11 | Champion Christian | 60 | 93 | Houston Christian (305) | Final | W | 33 |
| 4 | 2020-12-30 | Dallas Christian | 0 | 0 | Houston Christian (305) | Cancelled | - | - |
| 5 | 2021-01-02 | Northwestern State (315) | 93 | 99 | Houston Christian (305) | Final/OT | W | 6 |
| 6 | 2021-01-06 | Abilene Christian (245) | 66 | 63 | Houston Christian (305) | Final | L | -3 |
| 7 | 2021-01-20 | Nicholls State (250) | 92 | 83 | Houston Christian (305) | Final | L | -9 |
| 8 | 2021-01-23 | McNeese (63) | 74 | 71 | Houston Christian (305) | Final | L | -3 |
| 9 | 2021-01-30 | Houston Christian (305) | 0 | 0 | Texas A&M-Corpus Christi (208) | Cancelled | - | - |
| 10 | 2021-02-06 | Houston Christian (305) | 0 | 0 | Northwestern State (315) | Postponed | - | - |
| 11 | 2021-02-13 | Lamar (279) | 75 | 80 | Houston Christian (305) | Final | W | 5 |
| 12 | 2021-02-15 | Houston Christian (305) | 0 | 0 | Texas A&M-Corpus Christi (208) | Cancelled | - | - |
| 13 | 2021-02-20 | Sam Houston State (120) | 0 | 0 | Houston Christian (305) | Postponed | - | - |
| 14 | 2021-02-27 | Houston Christian (305) | 58 | 85 | McNeese (63) | Final | L | -27 |
| 15 | 2021-03-03 | Incarnate Word (280) | 67 | 72 | Houston Christian (305) | Final | W | 5 |
| 16 | 2021-03-06 | Texas A&M-Corpus Christi (208) | 94 | 70 | Houston Christian (305) | Final | L | -24 |