Schedule:
Please note: All rankings shown are the rankings of the teams on the date that they played one another
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2020-11-25 | UTSA (232) | 0 | 0 | Oklahoma (39) | Cancelled | - | - |
| 2 | 2020-11-27 | Texas Permian Basin | 71 | 97 | UTSA (344) | Final | W | 26 |
| 3 | 2020-11-28 | UTSA (344) | 64 | 81 | UTRGV (161) | Final | L | -17 |
| 4 | 2020-12-03 | UTSA (344) | 66 | 105 | Oklahoma (47) | Final | L | -39 |
| 5 | 2020-12-04 | Sul Ross | 62 | 91 | UTSA (308) | Final | W | 29 |
| 6 | 2020-12-16 | UTSA (344) | 61 | 73 | Oregon State (144) | Final | L | -12 |
| 7 | 2020-12-20 | Lady of the Lake | 70 | 102 | UTSA (344) | Final | W | 32 |
| 8 | 2020-12-22 | Lamar (279) | 66 | 88 | UTSA (344) | Final | W | 22 |
| 9 | 2021-01-01 | UTSA (344) | 86 | 95 | Rice (228) | Final | L | -9 |
| 10 | 2021-01-02 | UTSA (344) | 69 | 84 | Rice (228) | Final | L | -15 |
| 11 | 2021-01-08 | North Texas (125) | 77 | 70 | UTSA (344) | Final | L | -7 |
| 12 | 2021-01-09 | North Texas (125) | 69 | 77 | UTSA (344) | Final | W | 8 |
| 13 | 2021-01-15 | UTSA (344) | 66 | 77 | Louisiana Tech (185) | Final | L | -11 |
| 14 | 2021-01-16 | UTSA (344) | 66 | 82 | Louisiana Tech (185) | Final | L | -16 |
| 15 | 2021-01-22 | Southern Miss (201) | 64 | 70 | UTSA (344) | Final | W | 6 |
| 16 | 2021-01-23 | Southern Miss (201) | 72 | 78 | UTSA (344) | Final | W | 6 |
| 17 | 2021-01-28 | UTEP (274) | 79 | 86 | UTSA (344) | Final | W | 7 |
| 18 | 2021-01-30 | UTSA (344) | 51 | 69 | UTEP (274) | Final | L | -18 |
| 19 | 2021-02-05 | UTSA (344) | 87 | 80 | Florida International (214) | Final | W | 7 |
| 20 | 2021-02-06 | UTSA (344) | 90 | 47 | Florida International (214) | Final | W | 43 |
| 21 | 2021-02-12 | Florida Atlantic (128) | 80 | 84 | UTSA (344) | Final | W | 4 |
| 22 | 2021-02-13 | Florida Atlantic (128) | 75 | 86 | UTSA (344) | Final | W | 11 |
| 23 | 2021-02-19 | UTSA (186) | 0 | 0 | Charlotte (225) | Cancelled | - | - |
| 24 | 2021-02-20 | UTSA (344) | 0 | 0 | Charlotte (173) | Cancelled | - | - |
| 25 | 2021-02-21 | UTSA (344) | 0 | 0 | Charlotte (173) | Cancelled | - | - |
| 26 | 2021-02-26 | UAB (115) | 64 | 57 | UTSA (344) | Final | L | -7 |
| 27 | 2021-02-27 | UAB (115) | 79 | 96 | UTSA (344) | Final | W | 17 |
| 28 | 2021-03-04 | Southwestern Adventist | 43 | 123 | UTSA (344) | Final | W | 80 |
| 29 | 2021-03-10 | Charlotte (252) | 62 | 72 | UTSA (179) | Final | W | 10 |
| 30 | 2021-03-11 | UTSA (344) | 67 | 80 | Western Kentucky (154) | Final | L | -13 |