Schedule:
Please note: All rankings shown are the rankings of the teams on the date that they played one another
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2020-11-25 | Houston Baptist (344) | 45 | 69 | TCU (86) | Final | L | -24 |
| 2 | 2020-11-29 | Houston Baptist (344) | 77 | 100 | Arizona State (44) | Final | L | -23 |
| 3 | 2020-12-02 | Houston Baptist (336) | 75 | 102 | SMU (81) | Final | L | -27 |
| 4 | 2020-12-05 | Rice (60) | 86 | 64 | Houston Baptist (336) | Final | L | -22 |
| 5 | 2020-12-11 | Champion Christian | 60 | 93 | Houston Baptist (337) | Final | W | 33 |
| 6 | 2020-12-15 | Houston Baptist (323) | 79 | 90 | Rice (149) | Final | L | -11 |
| 7 | 2020-12-17 | Houston Baptist (323) | 55 | 85 | North Texas (223) | Final | L | -30 |
| 8 | 2020-12-19 | Houston Baptist (323) | 65 | 84 | Oklahoma (51) | Final | L | -19 |
| 9 | 2020-12-30 | Dallas Christian | 0 | 0 | Houston Baptist (333) | Cancelled | - | - |
| 10 | 2021-01-02 | Northwestern State (342) | 93 | 99 | Houston Baptist (333) | Final (OT) | W | 6 |
| 11 | 2021-01-06 | Abilene Christian (83) | 66 | 63 | Houston Baptist (326) | Final | L | -3 |
| 12 | 2021-01-09 | Houston Baptist (326) | 65 | 71 | Lamar (331) | Final | L | -6 |
| 13 | 2021-01-16 | Houston Baptist (330) | 80 | 87 | Sam Houston State (115) | Final | L | -7 |
| 14 | 2021-01-20 | Nicholls State (169) | 92 | 83 | Houston Baptist (328) | Final | L | -9 |
| 15 | 2021-01-23 | McNeese State (314) | 74 | 71 | Houston Baptist (328) | Final | L | -3 |
| 16 | 2021-01-27 | Houston Baptist (333) | 73 | 57 | Incarnate Word (289) | Final | W | 16 |
| 17 | 2021-01-30 | Houston Baptist (333) | 0 | 0 | Texas A&M-Corpus Christi (338) | Cancelled | - | - |
| 18 | 2021-02-10 | Houston Baptist (320) | 59 | 88 | Abilene Christian (81) | Final | L | -29 |
| 19 | 2021-02-13 | Lamar (325) | 75 | 80 | Houston Baptist (320) | Final | W | 5 |
| 20 | 2021-02-15 | Houston Baptist (318) | 0 | 0 | Texas A&M-Corpus Christi (339) | Cancelled | - | - |
| 21 | 2021-02-22 | Houston Baptist (318) | 80 | 86 | Northwestern State (300) | Final | L | -6 |
| 22 | 2021-02-24 | Houston Baptist (318) | 68 | 83 | Nicholls State (167) | Final | L | -15 |
| 23 | 2021-02-27 | Houston Baptist (318) | 58 | 85 | McNeese State (323) | Final | L | -27 |
| 24 | 2021-03-01 | Sam Houston State (113) | 83 | 70 | Houston Baptist (329) | Final | L | -13 |
| 25 | 2021-03-03 | Incarnate Word (315) | 67 | 72 | Houston Baptist (329) | Final | W | 5 |
| 26 | 2021-03-06 | Texas A&M-Corpus Christi (338) | 94 | 70 | Houston Baptist (329) | Final | L | -24 |
| 27 | 2021-03-09 | Houston Baptist (333) | 80 | 68 | Incarnate Word (328) | Final | W | 12 |
| 28 | 2021-03-10 | Houston Baptist (333) | 52 | 62 | Lamar (310) | Final | L | -10 |