Schedule:
Please note: All rankings shown are the rankings of the teams on the date that they played one another
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2020-11-26 | Kansas (19) | 90 | 102 | Gonzaga (11) | Final | L | -12 |
| 2 | 2020-11-26 | Gonzaga (2) | 102 | 90 | Kansas (1) | Final | L | -12 |
| 3 | 2020-11-27 | Saint Joseph's (99) | 72 | 94 | Kansas (19) | Final | W | 22 |
| 4 | 2020-12-01 | Kansas (19) | 65 | 62 | Kentucky (26) | Final | W | 3 |
| 5 | 2020-12-01 | Kentucky (105) | 62 | 65 | Kansas (124) | Final | W | 3 |
| 6 | 2020-12-03 | Washburn | 54 | 89 | Kansas (19) | Final | W | 35 |
| 7 | 2020-12-05 | North Dakota State (117) | 61 | 65 | Kansas (19) | Final | W | 4 |
| 8 | 2020-12-08 | Creighton (78) | 72 | 73 | Kansas (19) | Final | W | 1 |
| 9 | 2020-12-11 | Nebraska-Omaha (272) | 50 | 95 | Kansas (19) | Final | W | 45 |
| 10 | 2020-12-13 | Tarleton State (234) | 0 | 0 | Kansas (19) | Cancelled | - | - |
| 11 | 2020-12-13 | Tarleton State (240) | Kansas (78) | Cancelled | - | - | ||
| 12 | 2020-12-17 | Kansas (19) | 58 | 57 | Texas Tech (20) | Final | W | 1 |
| 13 | 2020-12-22 | West Virginia (50) | 65 | 79 | Kansas (19) | Final | W | 14 |
| 14 | 2021-01-02 | Texas (41) | 84 | 59 | Kansas (19) | Final | L | -25 |
| 15 | 2021-01-05 | Kansas (19) | 93 | 64 | TCU (32) | Final | W | 29 |
| 16 | 2021-01-09 | Oklahoma (47) | 59 | 63 | Kansas (19) | Final | W | 4 |
| 17 | 2021-01-12 | Kansas (19) | 70 | 75 | Oklahoma State (57) | Final | L | -5 |
| 18 | 2021-01-16 | Iowa State (7) | 0 | 0 | Kansas (19) | Postponed | - | - |
| 19 | 2021-01-18 | Kansas (19) | 69 | 77 | Baylor (58) | Final | L | -8 |
| 20 | 2021-01-23 | Kansas (19) | 68 | 75 | Oklahoma (47) | Final | L | -7 |
| 21 | 2021-01-28 | TCU (32) | 51 | 59 | Kansas (19) | Final | W | 8 |
| 22 | 2021-01-30 | Kansas (19) | 61 | 80 | Tennessee (18) | Final | L | -19 |
| 23 | 2021-02-02 | Kansas State (96) | 51 | 74 | Kansas (19) | Final | W | 23 |
| 24 | 2021-02-06 | Kansas (19) | 79 | 91 | West Virginia (50) | Final | L | -12 |
| 25 | 2021-02-08 | Oklahoma State (57) | 66 | 78 | Kansas (19) | Final | W | 12 |
| 26 | 2021-02-11 | Iowa State (7) | 64 | 97 | Kansas (19) | Final | W | 33 |
| 27 | 2021-02-13 | Kansas (19) | 64 | 50 | Iowa State (7) | Final | W | 14 |
| 28 | 2021-02-17 | Kansas (19) | 59 | 41 | Kansas State (96) | Final | W | 18 |
| 29 | 2021-02-20 | Texas Tech (20) | 61 | 67 | Kansas (19) | Final | W | 6 |
| 30 | 2021-02-23 | Kansas (19) | 72 | 75 | Texas (41) | Final/OT | L | -3 |
| 31 | 2021-02-27 | Baylor (58) | 58 | 71 | Kansas (19) | Final | W | 13 |
| 32 | 2021-03-04 | UTEP (274) | 62 | 67 | Kansas (19) | Final | W | 5 |
| 33 | 2021-03-11 | Oklahoma (47) | 62 | 69 | Kansas (19) | Final | W | 7 |
| 34 | 2021-03-12 | Texas (41) | 1 | 0 | Kansas (19) | Cancelled | L | -1 |
| 35 | 2021-03-12 | Texas (16) | 0 | 0 | Kansas (13) | Cancelled | - | - |
| 36 | 2021-03-20 | Eastern Washington (119) | 84 | 93 | Kansas (15) | Final | W | 9 |
| 37 | 2021-03-22 | USC (16) | 85 | 51 | Kansas (15) | Final | L | -34 |