Schedule:
Please note: All rankings shown are the rankings of the teams on the date that they played one another
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2020-11-25 | Drake (217) | 80 | 70 | Kansas State (96) | Final | L | -10 |
| 2 | 2020-11-27 | Colorado (73) | 76 | 58 | Kansas State (96) | Final | L | -18 |
| 3 | 2020-11-30 | UMKC (364) | 58 | 62 | Kansas State (96) | Final | W | 4 |
| 4 | 2020-12-05 | UNLV (105) | 68 | 58 | Kansas State (96) | Final | L | -10 |
| 5 | 2020-12-08 | Fort Hays State | 81 | 68 | Kansas State (297) | Final | L | -13 |
| 6 | 2020-12-11 | Kansas State (297) | 0 | 0 | Butler (107) | Cancelled | - | - |
| 7 | 2020-12-11 | Milwaukee (261) | 75 | 76 | Kansas State (96) | Final | W | 1 |
| 8 | 2020-12-15 | Kansas State (96) | 74 | 65 | Iowa State (7) | Final | W | 9 |
| 9 | 2020-12-19 | Baylor (58) | 100 | 69 | Kansas State (96) | Final | L | -31 |
| 10 | 2020-12-21 | Jacksonville (281) | 46 | 70 | Kansas State (96) | Final | W | 24 |
| 11 | 2020-12-29 | Nebraska-Omaha (272) | 58 | 60 | Kansas State (96) | Final | W | 2 |
| 12 | 2021-01-02 | TCU (32) | 67 | 60 | Kansas State (96) | Final | L | -7 |
| 13 | 2021-01-05 | Kansas State (96) | 71 | 82 | Texas Tech (20) | Final | L | -11 |
| 14 | 2021-01-09 | Oklahoma State (57) | 70 | 54 | Kansas State (96) | Final | L | -16 |
| 15 | 2021-01-13 | Iowa State (7) | 0 | 0 | Kansas State (96) | Postponed | - | - |
| 16 | 2021-01-16 | Kansas State (96) | 67 | 82 | Texas (41) | Final | L | -15 |
| 17 | 2021-01-19 | Kansas State (96) | 50 | 76 | Oklahoma (47) | Final | L | -26 |
| 18 | 2021-01-23 | West Virginia (50) | 69 | 47 | Kansas State (96) | Final | L | -22 |
| 19 | 2021-01-27 | Kansas State (96) | 59 | 107 | Baylor (58) | Final | L | -48 |
| 20 | 2021-01-30 | Texas A&M (39) | 68 | 61 | Kansas State (96) | Final | L | -7 |
| 21 | 2021-02-02 | Kansas State (96) | 51 | 74 | Kansas (19) | Final | L | -23 |
| 22 | 2021-02-06 | Texas Tech (20) | 73 | 62 | Kansas State (96) | Final | L | -11 |
| 23 | 2021-02-09 | Texas (41) | 80 | 77 | Kansas State (96) | Final | L | -3 |
| 24 | 2021-02-13 | Kansas State (96) | 60 | 67 | Oklahoma State (57) | Final | L | -7 |
| 25 | 2021-02-17 | Kansas (19) | 59 | 41 | Kansas State (96) | Final | L | -18 |
| 26 | 2021-02-20 | Kansas State (96) | 62 | 54 | TCU (32) | Final | W | 8 |
| 27 | 2021-02-23 | Oklahoma (47) | 57 | 62 | Kansas State (96) | Final | W | 5 |
| 28 | 2021-02-27 | Kansas State (96) | 43 | 65 | West Virginia (50) | Final | L | -22 |
| 29 | 2021-03-06 | Iowa State (7) | 56 | 61 | Kansas State (96) | Final | W | 5 |
| 30 | 2021-03-10 | Kansas State (197) | 71 | 50 | TCU (102) | Final | W | 21 |
| 31 | 2021-03-11 | Kansas State (96) | 68 | 74 | Baylor (58) | Final | L | -6 |