Schedule:
Please note: All rankings shown are the rankings of the teams on the date that they played one another
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2020-12-02 | Lipscomb (190) | 55 | 67 | Cincinnati (54) | Final | W | 12 |
| 2 | 2020-12-06 | Xavier (92) | 77 | 69 | Cincinnati (54) | Final | L | -8 |
| 3 | 2020-12-09 | Furman (157) | 73 | 78 | Cincinnati (54) | Final | W | 5 |
| 4 | 2020-12-12 | Cincinnati (54) | 56 | 65 | Tennessee (18) | Final | L | -9 |
| 5 | 2020-12-16 | South Florida (52) | 74 | 71 | Cincinnati (54) | Final | L | -3 |
| 6 | 2020-12-19 | Cincinnati (54) | 68 | 83 | Georgia (35) | Final | L | -15 |
| 7 | 2020-12-22 | Cincinnati (54) | 70 | 75 | Central Florida (43) | Final | L | -5 |
| 8 | 2021-01-02 | Tulsa (55) | 70 | 66 | Cincinnati (54) | Final | L | -4 |
| 9 | 2021-01-07 | Cincinnati (54) | 76 | 69 | SMU (45) | Final | W | 7 |
| 10 | 2021-01-10 | Cincinnati (54) | 76 | 82 | Wichita State (76) | Final | L | -6 |
| 11 | 2021-01-13 | East Carolina (252) | 0 | 0 | Cincinnati (54) | Cancelled | - | - |
| 12 | 2021-01-20 | Cincinnati (54) | 0 | 0 | Temple (169) | Postponed | - | - |
| 13 | 2021-01-23 | Cincinnati (132) | 0 | 0 | Houston (5) | Cancelled | - | - |
| 14 | 2021-01-27 | Wichita State (76) | 0 | 0 | Cincinnati (54) | Cancelled | - | - |
| 15 | 2021-01-30 | Cincinnati (54) | 0 | 0 | South Florida (52) | Cancelled | - | - |
| 16 | 2021-02-04 | Cincinnati (54) | 63 | 60 | Temple (169) | Final | W | 3 |
| 17 | 2021-02-07 | Cincinnati (54) | 64 | 61 | Tulane (167) | Final | W | 3 |
| 18 | 2021-02-11 | Cincinnati (54) | 0 | 0 | Memphis (136) | Cancelled | - | - |
| 19 | 2021-02-12 | Temple (169) | 69 | 71 | Cincinnati (54) | Final | W | 2 |
| 20 | 2021-02-14 | Central Florida (43) | 68 | 69 | Cincinnati (54) | Final | W | 1 |
| 21 | 2021-02-21 | Cincinnati (54) | 52 | 90 | Houston (5) | Final | L | -38 |
| 22 | 2021-02-24 | Cincinnati (54) | 70 | 69 | Tulsa (55) | Final | W | 1 |
| 23 | 2021-02-26 | Tulane (167) | 71 | 91 | Cincinnati (54) | Final | W | 20 |
| 24 | 2021-02-28 | Memphis (136) | 80 | 74 | Cincinnati (54) | Final | L | -6 |
| 25 | 2021-03-04 | SMU | 0 | 0 | Cincinnati | Cancelled | - | - |
| 26 | 2021-03-04 | Vanderbilt (17) | 78 | 64 | Cincinnati (54) | Final | L | -14 |
| 27 | 2021-03-07 | Cincinnati (54) | 82 | 69 | East Carolina (252) | Final | W | 13 |
| 28 | 2021-03-12 | Cincinnati (54) | 74 | 71 | SMU (45) | Final | W | 3 |
| 29 | 2021-03-13 | Cincinnati (113) | 60 | 59 | Wichita State (41) | Final | W | 1 |
| 30 | 2021-03-14 | Cincinnati (54) | 54 | 91 | Houston (5) | Final | L | -37 |