Schedule:
Please note: All rankings shown are the rankings of the teams on the date that they played one another
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2020-11-28 | Oklahoma (47) | 0 | 0 | Central Florida (43) | Cancelled | - | - |
| 2 | 2020-11-30 | Auburn (37) | 55 | 63 | Central Florida (43) | Final | W | 8 |
| 3 | 2020-12-06 | Central Florida (43) | 58 | 80 | Michigan (1) | Final | L | -22 |
| 4 | 2020-12-15 | Central Florida (43) | 0 | 0 | Houston (5) | Postponed | - | - |
| 5 | 2020-12-19 | Central Florida (43) | 86 | 74 | Florida State (64) | Final | W | 12 |
| 6 | 2020-12-22 | Cincinnati (54) | 70 | 75 | Central Florida (43) | Final | W | 5 |
| 7 | 2020-12-26 | Houston (5) | 63 | 54 | Central Florida (43) | Final | L | -9 |
| 8 | 2020-12-30 | Tulane (167) | 0 | 0 | Central Florida (43) | Postponed | - | - |
| 9 | 2021-01-02 | Central Florida (43) | 61 | 68 | South Florida (52) | Final | L | -7 |
| 10 | 2021-01-05 | Memphis (136) | 0 | 0 | Central Florida (43) | Cancelled | - | - |
| 11 | 2021-01-09 | Central Florida (43) | 0 | 0 | Tulsa (55) | Postponed | - | - |
| 12 | 2021-01-14 | Central Florida (43) | 55 | 62 | Temple (169) | Final | L | -7 |
| 13 | 2021-01-17 | Central Florida (43) | 58 | 75 | Houston (5) | Final | L | -17 |
| 14 | 2021-01-23 | SMU (45) | 78 | 65 | Central Florida (43) | Final | L | -13 |
| 15 | 2021-01-27 | East Carolina (252) | 64 | 71 | Central Florida (43) | Final | W | 7 |
| 16 | 2021-01-30 | Central Florida (43) | 88 | 93 | Wichita State (76) | Final/OT | L | -5 |
| 17 | 2021-02-01 | Central Florida (43) | 69 | 96 | Memphis (136) | Final | L | -27 |
| 18 | 2021-02-03 | Central Florida (43) | 61 | 75 | Memphis (136) | Final | L | -14 |
| 19 | 2021-02-06 | Central Florida (43) | 65 | 58 | Tulsa (55) | Final | W | 7 |
| 20 | 2021-02-10 | Wichita State (76) | 61 | 60 | Central Florida (43) | Final | L | -1 |
| 21 | 2021-02-12 | Tulane (167) | 49 | 53 | Central Florida (43) | Final | W | 4 |
| 22 | 2021-02-14 | Central Florida (43) | 68 | 69 | Cincinnati (54) | Final | L | -1 |
| 23 | 2021-02-17 | South Florida (52) | 65 | 81 | Central Florida (43) | Final | W | 16 |
| 24 | 2021-02-20 | Central Florida (43) | 84 | 81 | Tulane (167) | Final | W | 3 |
| 25 | 2021-02-23 | Central Florida (43) | 0 | 0 | SMU (45) | Cancelled | - | - |
| 26 | 2021-02-27 | Temple (169) | 0 | 0 | Central Florida (43) | Cancelled | - | - |
| 27 | 2021-03-02 | Tulsa (55) | 69 | 73 | Central Florida (43) | Final | W | 4 |
| 28 | 2021-03-04 | Central Florida (43) | 64 | 60 | East Carolina (252) | Final | W | 4 |
| 29 | 2021-03-11 | East Carolina (252) | 62 | 72 | Central Florida (43) | Final | W | 10 |
| 30 | 2021-03-12 | Central Florida (43) | 62 | 70 | Memphis (136) | Final | L | -8 |
| 31 | 2021-03-19 | Central Florida (100) | 73 | 58 | Virginia Commonwealth (38) | Final | W | 15 |