Schedule:
| Game | Date | Away Team (Rank) | Away Score | Home Team (Rank) | Home Score | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2021-09-02 | The Citadel | 14 | Coastal Carolina | 52 | Final | L | -38 |
| 2 | 2021-09-11 | Charleston Southern | 38 | The Citadel | 21 | Final | L | -17 |
| 3 | 2021-09-18 | North Greenville | 13 | The Citadel | 45 | Final | W | 32 |
| 4 | 2021-10-02 | Virginia Military | 24 | The Citadel | 35 | Final | W | 11 |
| 5 | 2021-10-09 | The Citadel | 21 | East Tennessee State | 48 | Final | L | -27 |
| 6 | 2021-10-16 | The Citadel | 14 | Furman | 24 | Final | L | -10 |
| 7 | 2021-10-23 | Western Carolina | 45 | The Citadel | 31 | Final | L | -14 |
| 8 | 2021-10-30 | Mercer | 34 | The Citadel | 7 | Final | L | -27 |
| 9 | 2021-11-06 | The Citadel | 14 | Samford | 35 | Final | L | -21 |
| 10 | 2021-11-13 | Wofford | 44 | The Citadel | 45 | Final(OT) | W | 1 |
| 11 | 2021-11-20 | The Citadel | 24 | Chattanooga | 21 | Final | W | 3 |