Schedule:
| Game | Date | Away Team (Rank) | Away Score | Home Team (Rank) | Home Score | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2015-09-05 | Stanford (36) | 6 | Northwestern (79) | 16 | Final | W | 10 |
| 2 | 2015-09-12 | Eastern Illinois | 0 | Northwestern | 41 | Final | W | 41 |
| 3 | 2015-09-19 | Northwestern (28) | 19 | Duke (33) | 10 | Final | W | 9 |
| 4 | 2015-09-26 | Ball State (71) | 19 | Northwestern (10) | 24 | Final | W | 5 |
| 5 | 2015-10-03 | Minnesota (38) | 0 | Northwestern (5) | 27 | Final | W | 27 |
| 6 | 2015-10-10 | Northwestern (2) | 0 | Michigan (13) | 38 | Final | L | -38 |
| 7 | 2015-10-17 | Iowa (13) | 40 | Northwestern (17) | 10 | Final | L | -30 |
| 8 | 2015-10-24 | Northwestern (24) | 30 | Nebraska (59) | 28 | Final | W | 2 |
| 9 | 2015-11-07 | Penn State (34) | 21 | Northwestern (24) | 23 | Final | W | 2 |
| 10 | 2015-11-14 | Purdue (101) | 14 | Northwestern (20) | 21 | Final | W | 7 |
| 11 | 2015-11-21 | Northwestern (23) | 13 | Wisconsin (24) | 7 | Final | W | 6 |
| 12 | 2015-11-28 | Northwestern (16) | 24 | Illinois (67) | 14 | Final | W | 10 |
| 13 | 2016-01-01 | Northwestern (15) | 6 | Tennessee (26) | 45 | Final | L | -39 |