Schedule:
| Game | Date | Away Team (Rank) | Away Score | Home Team (Rank) | Home Score | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2016-09-03 | North Carolina Central | 6 | Duke | 49 | Final | L | -43 |
| 2 | 2016-09-10 | North Carolina Central | 21 | Western Michigan | 70 | Final | L | -49 |
| 3 | 2016-09-17 | St. Augustine's | 7 | North Carolina Central | 65 | Final | W | 58 |
| 4 | 2016-09-24 | North Carolina Central | 34 | Norfolk State | 31 | Final | W | 3 |
| 5 | 2016-10-01 | North Carolina Central | 31 | Bethune-Cookman | 14 | Final | W | 17 |
| 6 | 2016-10-08 | Florida A&M | 13 | North Carolina Central | 17 | Final | W | 4 |
| 7 | 2016-10-15 | Savannah State | 3 | North Carolina Central | 33 | Final | W | 30 |
| 8 | 2016-10-22 | North Carolina Central | 21 | Morgan State | 17 | Final | W | 4 |
| 9 | 2016-11-05 | North Carolina Central | 38 | Delaware State | 19 | Final | W | 19 |
| 10 | 2016-11-12 | Howard | 21 | North Carolina Central | 30 | Final | W | 9 |
| 11 | 2016-11-19 | North Carolina A&T | 21 | North Carolina Central | 42 | Final | W | 21 |
| 12 | 2016-12-17 | North Carolina Central | 9 | Grambling | 10 | Final | L | -1 |