Schedule:
| Game | Date | Away Team (Rank) | Away Score | Home Team (Rank) | Home Score | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2016-09-03 | Howard | 13 | Maryland | 52 | Final | L | -39 |
| 2 | 2016-09-10 | Howard | 14 | Rutgers | 52 | Final | L | -38 |
| 3 | 2016-09-17 | Hampton | 34 | Howard | 7 | Final | L | -27 |
| 4 | 2016-09-24 | Howard | 24 | Morgan State | 28 | Final | L | -4 |
| 5 | 2016-10-01 | Howard | 33 | Norfolk State | 28 | Final | W | 5 |
| 6 | 2016-10-08 | Monmouth | 59 | Howard | 27 | Final | L | -32 |
| 7 | 2016-10-15 | South Carolina State | 14 | Howard | 9 | Final | L | -5 |
| 8 | 2016-10-22 | North Carolina A&T | 34 | Howard | 7 | Final | L | -27 |
| 9 | 2016-10-29 | Howard (242) | 27 | Savannah State (229) | 31 | Final | L | -4 |
| 10 | 2016-11-12 | Howard | 21 | North Carolina Central | 30 | Final | L | -9 |
| 11 | 2016-11-19 | Delaware State (252) | 21 | Howard (245) | 26 | Final | W | 5 |