Schedule:
| Game | Date | Away Team (Rank) | Away Score | Home Team (Rank) | Home Score | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2016-09-04 | Alcorn State | 0 | Bethune-Cookman | 0 | Canceled | - | - |
| 2 | 2016-09-10 | Bethune-Cookman | 20 | North Texas | 41 | Final | L | -21 |
| 3 | 2016-09-17 | Tennessee State | 31 | Bethune-Cookman | 24 | Final | L | -7 |
| 4 | 2016-09-24 | Bethune-Cookman | 10 | Savannah State | 16 | Final/OT | L | -6 |
| 5 | 2016-10-01 | North Carolina Central | 31 | Bethune-Cookman | 14 | Final | L | -17 |
| 6 | 2016-10-08 | Bethune-Cookman | 0 | South Carolina State | 0 | Postponed | - | - |
| 7 | 2016-10-15 | North Carolina A&T | 52 | Bethune-Cookman | 35 | Final | L | -17 |
| 8 | 2016-10-22 | Bethune-Cookman | 21 | Norfolk State | 14 | Final | W | 7 |
| 9 | 2016-10-29 | Delaware State (252) | 10 | Bethune-Cookman (227) | 41 | Final | W | 31 |
| 10 | 2016-11-05 | Bethune-Cookman (220) | 41 | Morgan State (242) | 10 | Final | W | 31 |
| 11 | 2016-11-19 | Bethune-Cookman (209) | 39 | Florida A&M (226) | 19 | Final | W | 20 |
| 12 | 2016-11-26 | Bethune-Cookman | 7 | South Carolina State | 28 | Final | L | -21 |