Schedule:
| Game | Date | Away Team (Rank) | Away Score | Home Team (Rank) | Home Score | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2022-09-03 | Memphis (82) | 23 | Mississippi State (80) | 49 | Final | W | 26 |
| 2 | 2022-09-10 | Mississippi State (80) | 39 | Arizona (154) | 17 | Final | W | 22 |
| 3 | 2022-09-17 | Mississippi State (38) | 16 | LSU (34) | 31 | Final | L | -15 |
| 4 | 2022-09-24 | Bowling Green (117) | 14 | Mississippi State (20) | 45 | Final | W | 31 |
| 5 | 2022-10-01 | Texas A&M (87) | 24 | Mississippi State (18) | 42 | Final | W | 18 |
| 6 | 2022-10-08 | Arkansas (59) | 17 | Mississippi State (19) | 40 | Final | W | 23 |
| 7 | 2022-10-15 | Mississippi State (25) | 17 | Kentucky (28) | 27 | Final | L | -10 |
| 8 | 2022-10-22 | Mississippi State (26) | 6 | Alabama (7) | 30 | Final | L | -24 |
| 9 | 2022-11-05 | Auburn (71) | 33 | Mississippi State (24) | 39 | Final(OT) | W | 6 |
| 10 | 2022-11-12 | Georgia (1) | 45 | Mississippi State (25) | 19 | Final | L | -26 |
| 11 | 2022-11-19 | East Tennessee State (224) | 7 | Mississippi State (21) | 56 | Final | W | 49 |
| 12 | 2022-11-24 | Mississippi State (19) | 24 | Ole Miss (21) | 22 | Final | W | 2 |
| 13 | 2023-01-02 | Mississippi State (19) | 19 | Illinois (30) | 10 | Final | W | 9 |