Schedule:
| Game | Date | Away Team (Rank) | Away Score | Home Team (Rank) | Home Score | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2022-09-03 | Memphis (82) | 23 | Mississippi State (80) | 49 | Final | L | -26 |
| 2 | 2022-09-10 | Memphis (82) | 37 | Navy (83) | 13 | Final | W | 24 |
| 3 | 2022-09-17 | Arkansas State (93) | 32 | Memphis (62) | 44 | Final | W | 12 |
| 4 | 2022-09-24 | North Texas (102) | 34 | Memphis (51) | 44 | Final | W | 10 |
| 5 | 2022-10-01 | Temple (99) | 3 | Memphis (30) | 24 | Final | W | 21 |
| 6 | 2022-10-07 | Houston (45) | 33 | Memphis (44) | 32 | Final | L | -1 |
| 7 | 2022-10-15 | Memphis (57) | 45 | East Carolina (62) | 47 | Final(4OT) | L | -2 |
| 8 | 2022-10-22 | Memphis (69) | 28 | Tulane (29) | 38 | Final | L | -10 |
| 9 | 2022-11-05 | Central Florida (21) | 35 | Memphis (69) | 28 | Final | L | -7 |
| 10 | 2022-11-10 | Tulsa (116) | 10 | Memphis (68) | 26 | Final | W | 16 |
| 11 | 2022-11-19 | North Alabama (253) | 0 | Memphis (65) | 59 | Final | W | 59 |
| 12 | 2022-11-26 | Memphis (68) | 31 | SMU (50) | 34 | Final | L | -3 |
| 13 | 2022-12-27 | Memphis (68) | 38 | Utah State (110) | 10 | Final | W | 28 |