Schedule:
| Game | Date | Away Team (Rank) | Away Score | Home Team (Rank) | Home Score | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2022-09-03 | Wofford (238) | 0 | Chattanooga (159) | 31 | Final | W | 31 |
| 2 | 2022-09-10 | Chattanooga (159) | 38 | Eastern Illinois (246) | 20 | Final | W | 18 |
| 3 | 2022-09-17 | North Alabama (238) | 14 | Chattanooga (138) | 41 | Final | W | 27 |
| 4 | 2022-09-22 | Chattanooga (155) | 0 | Illinois (29) | 31 | Final | L | -31 |
| 5 | 2022-10-01 | Chattanooga (152) | 24 | East Tennessee State (220) | 16 | Final | W | 8 |
| 6 | 2022-10-15 | Virginia Military (241) | 13 | Chattanooga (148) | 41 | Final | W | 28 |
| 7 | 2022-10-22 | Mercer (141) | 21 | Chattanooga (137) | 41 | Final | W | 20 |
| 8 | 2022-10-29 | Chattanooga (149) | 20 | Furman (152) | 24 | Final | L | -4 |
| 9 | 2022-11-05 | Chattanooga (150) | 31 | The Citadel (221) | 21 | Final | W | 10 |
| 10 | 2022-11-12 | Samford (125) | 35 | Chattanooga (156) | 24 | Final | L | -11 |
| 11 | 2022-11-19 | Chattanooga (166) | 29 | Western Carolina (186) | 32 | Final | L | -3 |