Schedule:
Please note: All rankings shown are the rankings of the teams on the date that they played one another
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2020-11-28 | William & Mary (141) | 78 | 86 | Old Dominion (254) | Final | L | -8 |
| 2 | 2020-11-30 | William & Mary (141) | 0 | 0 | North Carolina State (44) | Cancelled | - | - |
| 3 | 2020-12-03 | Hampton (260) | 0 | 0 | William & Mary (141) | Postponed | - | - |
| 4 | 2020-12-05 | William & Mary (305) | George Washington (294) | Cancelled | - | - | ||
| 5 | 2020-12-09 | William & Mary (141) | 0 | 0 | Norfolk State (322) | Cancelled | - | - |
| 6 | 2020-12-09 | William & Mary (255) | Norfolk State (133) | Cancelled | - | - | ||
| 7 | 2020-12-13 | William & Mary (141) | 0 | 0 | Virginia (14) | Postponed | - | - |
| 8 | 2020-12-14 | William & Mary (141) | 85 | 84 | George Washington (104) | Final/OT | W | 1 |
| 9 | 2020-12-16 | William & Mary (141) | 75 | 58 | Hampton (260) | Final | W | 17 |
| 10 | 2020-12-19 | High Point (69) | 71 | 49 | William & Mary (141) | Final | L | -22 |
| 11 | 2020-12-22 | Fairfield (341) | William & Mary (274) | Cancelled | - | - | ||
| 12 | 2020-12-22 | William & Mary (141) | 40 | 76 | Virginia (14) | Final | L | -36 |
| 13 | 2021-01-02 | William & Mary (141) | 56 | 61 | Hofstra (98) | Final | L | -5 |
| 14 | 2021-01-03 | William & Mary (141) | 73 | 82 | Hofstra (98) | Final | L | -9 |
| 15 | 2021-01-09 | Delaware (287) | 62 | 67 | William & Mary (141) | Final | W | 5 |
| 16 | 2021-01-10 | Delaware (287) | 0 | 0 | William & Mary (141) | Cancelled | - | - |
| 17 | 2021-01-16 | William & Mary (141) | 58 | 82 | Drexel (215) | Final | L | -24 |
| 18 | 2021-01-17 | William & Mary (141) | 69 | 64 | Drexel (215) | Final | W | 5 |
| 19 | 2021-01-23 | Charleston (246) | 0 | 0 | William & Mary (268) | Cancelled | - | - |
| 20 | 2021-01-23 | Drexel (215) | 79 | 64 | William & Mary (141) | Final | L | -15 |
| 21 | 2021-01-24 | Charleston (123) | 0 | 0 | William & Mary (141) | Postponed | - | - |
| 22 | 2021-01-30 | William & Mary (141) | 84 | 74 | Towson (152) | Final | W | 10 |
| 23 | 2021-01-31 | William & Mary (141) | 75 | 74 | Towson (152) | Final | W | 1 |
| 24 | 2021-02-06 | James Madison (202) | 0 | 0 | William & Mary (141) | Postponed | - | - |
| 25 | 2021-02-07 | James Madison (202) | 0 | 0 | William & Mary (141) | Cancelled | - | - |
| 26 | 2021-02-13 | William & Mary (141) | 0 | 0 | UNC-Wilmington (90) | Postponed | - | - |
| 27 | 2021-02-14 | William & Mary (141) | 0 | 0 | UNC-Wilmington (90) | Cancelled | - | - |
| 28 | 2021-02-18 | William & Mary (141) | 0 | 0 | Elon (232) | Postponed | - | - |
| 29 | 2021-02-20 | Elon (232) | 75 | 54 | William & Mary (141) | Final | L | -21 |
| 30 | 2021-02-22 | William & Mary (141) | 54 | 73 | Elon (232) | Final | L | -19 |
| 31 | 2021-02-27 | Northeastern (300) | 0 | 0 | William & Mary (141) | Cancelled | - | - |
| 32 | 2021-02-28 | Northeastern (300) | 0 | 0 | William & Mary (141) | Cancelled | - | - |
| 33 | 2021-03-06 | UNC-Wilmington (90) | 60 | 73 | William & Mary (141) | Final | W | 13 |
| 34 | 2021-03-07 | William & Mary (141) | 47 | 63 | Northeastern (300) | Final | L | -16 |