Schedule:
Please note: All rankings shown are the rankings of the teams on the date that they played one another
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2020-12-01 | Hampton (260) | 82 | 78 | George Washington (104) | Final | W | 4 |
| 2 | 2020-12-03 | Hampton (260) | 0 | 0 | William & Mary (141) | Postponed | - | - |
| 3 | 2020-12-07 | Hampton (260) | 64 | 76 | Norfolk State (322) | Final | L | -12 |
| 4 | 2020-12-10 | Regent | 0 | 0 | Hampton (260) | Cancelled | - | - |
| 5 | 2020-12-10 | Regent | Hampton (94) | Cancelled | - | - | ||
| 6 | 2020-12-13 | Hampton (260) | 64 | 79 | Virginia Military (357) | Final | L | -15 |
| 7 | 2020-12-16 | William & Mary (141) | 75 | 58 | Hampton (260) | Final | L | -17 |
| 8 | 2020-12-18 | Hampton (260) | 76 | 81 | Howard (211) | Final | L | -5 |
| 9 | 2020-12-21 | Hampton (260) | 67 | 55 | Charleston Southern (262) | Final | W | 12 |
| 10 | 2020-12-22 | Hampton (260) | 70 | 68 | Charleston Southern (262) | Final | W | 2 |
| 11 | 2020-12-30 | Gardner-Webb (363) | 69 | 80 | Hampton (260) | Final | W | 11 |
| 12 | 2020-12-31 | Gardner-Webb (363) | 80 | 69 | Hampton (260) | Final | L | -11 |
| 13 | 2021-01-04 | Hampton (260) | 66 | 79 | Radford (255) | Final | L | -13 |
| 14 | 2021-01-05 | Hampton (260) | 65 | 76 | Radford (255) | Final | L | -11 |
| 15 | 2021-01-09 | UNC-Asheville (244) | 71 | 73 | Hampton (260) | Final | W | 2 |
| 16 | 2021-01-10 | UNC-Asheville (244) | 85 | 77 | Hampton (260) | Final | L | -8 |
| 17 | 2021-01-14 | Hampton (260) | 69 | 68 | South Carolina Upstate (293) | Final | W | 1 |
| 18 | 2021-01-15 | Hampton (260) | 84 | 74 | South Carolina Upstate (293) | Final | W | 10 |
| 19 | 2021-01-19 | Campbell (251) | 0 | 0 | Hampton (296) | Cancelled | - | - |
| 20 | 2021-01-20 | Campbell (251) | 0 | 0 | Hampton (296) | Cancelled | - | - |
| 21 | 2021-01-24 | Hampton (260) | 0 | 0 | Winthrop (133) | Cancelled | - | - |
| 22 | 2021-01-25 | Hampton (260) | 0 | 0 | Winthrop (133) | Cancelled | - | - |
| 23 | 2021-01-29 | High Point (305) | 0 | 0 | Hampton (299) | Cancelled | - | - |
| 24 | 2021-01-30 | High Point (305) | 0 | 0 | Hampton (299) | Cancelled | - | - |
| 25 | 2021-02-04 | Hampton (296) | 0 | 0 | Longwood (307) | Cancelled | - | - |
| 26 | 2021-02-05 | Hampton (296) | 0 | 0 | Longwood (307) | Cancelled | - | - |
| 27 | 2021-02-07 | High Point (69) | 72 | 58 | Hampton (260) | Final | L | -14 |
| 28 | 2021-02-08 | High Point (69) | 71 | 76 | Hampton (260) | Final | W | 5 |
| 29 | 2021-02-11 | Presbyterian (264) | 85 | 70 | Hampton (260) | Final | L | -15 |
| 30 | 2021-02-12 | Presbyterian (264) | 57 | 62 | Hampton (260) | Final | W | 5 |
| 31 | 2021-02-15 | Hampton (260) | 73 | 83 | Longwood (269) | Final | L | -10 |
| 32 | 2021-02-18 | Campbell (191) | 76 | 57 | Hampton (260) | Final | L | -19 |
| 33 | 2021-02-19 | Campbell (191) | 73 | 68 | Hampton (260) | Final | L | -5 |
| 34 | 2021-02-21 | Hampton (260) | 0 | 0 | Longwood (269) | Cancelled | - | - |
| 35 | 2021-02-23 | Hampton (260) | 0 | 0 | Winthrop (133) | Cancelled | - | - |
| 36 | 2021-02-24 | Hampton | 0 | 0 | Winthrop | Cancelled | - | - |
| 37 | 2021-02-24 | Hampton (260) | 74 | 68 | Longwood (269) | Final | W | 6 |
| 38 | 2021-02-27 | Presbyterian (264) | 65 | 67 | Hampton (260) | Final | W | 2 |
| 39 | 2021-03-01 | Hampton (310) | 52 | 67 | Radford (233) | Final | L | -15 |