Schedule:
Please note: All rankings shown are the rankings of the teams on the date that they played one another
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2020-11-25 | Charleston (123) | 60 | 79 | North Carolina (22) | Final | L | -19 |
| 2 | 2020-11-28 | Limestone | 59 | 99 | Charleston (123) | Final | W | 40 |
| 3 | 2020-12-02 | Richmond (166) | 0 | 0 | Charleston (123) | Cancelled | - | - |
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Charleston (268) | Cancelled | - | - |
| 5 | 2020-12-05 | Furman (157) | 81 | 57 | Charleston (123) | Final | L | -24 |
| 6 | 2020-12-09 | Marshall (155) | 84 | 72 | Charleston (123) | Final | L | -12 |
| 7 | 2020-12-11 | South Carolina State (355) | 63 | 90 | Charleston (123) | Final | W | 27 |
| 8 | 2020-12-18 | Western Carolina (223) | 76 | 70 | Charleston (123) | Final/OT | L | -6 |
| 9 | 2020-12-21 | Charleston (123) | 55 | 72 | Georgia State (299) | Final | L | -17 |
| 10 | 2021-01-02 | Charleston (123) | 67 | 70 | Delaware (287) | Final | L | -3 |
| 11 | 2021-01-03 | Charleston (123) | 66 | 59 | Delaware (287) | Final | W | 7 |
| 12 | 2021-01-09 | Drexel (215) | 60 | 61 | Charleston (123) | Final | W | 1 |
| 13 | 2021-01-10 | Drexel (215) | 68 | 73 | Charleston (123) | Final | W | 5 |
| 14 | 2021-01-16 | Northeastern (300) | 67 | 62 | Charleston (123) | Final | L | -5 |
| 15 | 2021-01-17 | Northeastern (300) | 68 | 66 | Charleston (123) | Final | L | -2 |
| 16 | 2021-01-23 | Charleston (246) | 0 | 0 | William & Mary (268) | Cancelled | - | - |
| 17 | 2021-01-24 | Charleston (123) | 0 | 0 | William & Mary (141) | Postponed | - | - |
| 18 | 2021-01-30 | Charleston (123) | 0 | 0 | James Madison (202) | Cancelled | - | - |
| 19 | 2021-01-31 | Charleston (239) | 0 | 0 | James Madison (161) | Cancelled | - | - |
| 20 | 2021-02-06 | Towson (152) | 88 | 90 | Charleston (123) | Final/2OT | W | 2 |
| 21 | 2021-02-07 | Towson (152) | 53 | 66 | Charleston (123) | Final | W | 13 |
| 22 | 2021-02-13 | Elon (232) | 53 | 71 | Charleston (123) | Final | W | 18 |
| 23 | 2021-02-14 | Elon (232) | 66 | 55 | Charleston (123) | Final | L | -11 |
| 24 | 2021-02-20 | Charleston (221) | 0 | 0 | Hofstra (153) | Cancelled | - | - |
| 25 | 2021-02-20 | Columbus State | 83 | 86 | Charleston (123) | Final/OT | W | 3 |
| 26 | 2021-02-21 | Charleston (229) | 0 | 0 | Hofstra (156) | Cancelled | - | - |
| 27 | 2021-02-25 | Charleston (123) | 0 | 0 | UNC-Wilmington (90) | Cancelled | - | - |
| 28 | 2021-03-07 | Drexel (215) | 80 | 75 | Charleston (123) | Final | L | -5 |