NCAA Women's Basketball Schedule:
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2021-11-09 | North Florida (196) | 50 | 78 | Florida State (46) | Final | L | -28 |
| 2 | 2021-11-11 | Warner | 40 | 92 | North Florida (302) | Final | W | 52 |
| 3 | 2021-11-13 | Trinity Baptist | 31 | 126 | North Florida (196) | Final | W | 95 |
| 4 | 2021-11-18 | Webber Int'l | 59 | 83 | North Florida (302) | Final | W | 24 |
| 5 | 2021-11-21 | Florida Atlantic (98) | 79 | 85 | North Florida (178) | Final/OT | W | 6 |
| 6 | 2021-11-24 | North Florida (112) | 72 | 84 | Clemson (100) | Final | L | -12 |
| 7 | 2021-11-27 | North Florida (112) | 86 | 76 | Charleston (69) | Final | W | 10 |
| 8 | 2021-11-30 | North Florida (134) | 65 | 72 | Auburn (154) | Final | L | -7 |
| 9 | 2021-12-04 | North Florida (302) | 51 | 53 | Florida International (139) | Final | L | -2 |
| 10 | 2021-12-08 | North Florida (192) | 40 | 69 | Georgia (15) | Final | L | -29 |
| 11 | 2021-12-12 | Bethune-Cookman (332) | 47 | 60 | North Florida (192) | Final | W | 13 |
| 12 | 2021-12-21 | North Florida (186) | 0 | 0 | Miami (86) | Postponed | - | - |
| 13 | 2021-12-30 | North Florida (184) | 64 | 54 | Florida A&M (352) | Final | W | 10 |
| 14 | 2022-01-05 | North Florida (302) | 57 | 88 | Florida Gulf Coast (172) | Final | L | -31 |
| 15 | 2022-01-08 | Stetson (170) | 73 | 62 | North Florida (302) | Final | L | -11 |
| 16 | 2022-01-12 | North Florida (302) | 50 | 61 | Liberty (144) | Final | L | -11 |
| 17 | 2022-01-15 | Jacksonville (221) | 52 | 50 | North Florida (227) | Final | L | -2 |
| 18 | 2022-01-19 | Kennesaw State (246) | 49 | 66 | North Florida (302) | Final | W | 17 |
| 19 | 2022-01-22 | North Florida (242) | 78 | 64 | Eastern Kentucky (278) | Final | W | 14 |
| 20 | 2022-01-27 | Central Arkansas (131) | 56 | 53 | North Florida (302) | Final | L | -3 |
| 21 | 2022-01-29 | Lipscomb (268) | 75 | 83 | North Florida (211) | Final/OT | W | 8 |
| 22 | 2022-02-03 | North Florida (223) | 58 | 66 | Jacksonville State (135) | Final | L | -8 |
| 23 | 2022-02-05 | North Florida (302) | 65 | 70 | North Alabama (230) | Final | L | -5 |
| 24 | 2022-02-09 | Bellarmine (358) | 63 | 85 | North Florida (302) | Final | W | 22 |
| 25 | 2022-02-12 | North Florida (239) | 57 | 63 | Kennesaw State (268) | Final | L | -6 |
| 26 | 2022-02-17 | Liberty (50) | 56 | 38 | North Florida (246) | Final | L | -18 |
| 27 | 2022-02-19 | Florida Gulf Coast (30) | 63 | 52 | North Florida (246) | Final | L | -11 |
| 28 | 2022-02-24 | North Florida (250) | 72 | 54 | Jacksonville (204) | Final | W | 18 |
| 29 | 2022-02-26 | North Florida (250) | 47 | 59 | Stetson (134) | Final | L | -12 |
| 30 | 2022-03-02 | North Florida (242) | 60 | 42 | Lipscomb (298) | Final | W | 18 |
| 31 | 2022-03-06 | North Florida (242) | 60 | 71 | Florida Gulf Coast (24) | Final | L | -11 |