Schedule:
| Game | Date | Away Team (Rank) | Away Score | Home Team (Rank) | Home Score | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2021-09-25 | Virginia Lynchburg | 7 | Duquesne | 56 | Final | L | -49 |
| 2 | 2021-10-09 | Virginia Lynchburg | 6 | Delaware State | 56 | Final | L | -50 |
| 3 | 2021-10-16 | Virginia Lynchburg | 14 | Norfolk State | 42 | Final | L | -28 |
| 4 | 2021-10-23 | Virginia Lynchburg | 13 | Tennessee Tech | 56 | Final | L | -43 |
| 5 | 2021-11-20 | Virginia Lynchburg | 6 | Howard | 56 | Final | L | -50 |