Schedule:
| Game | Date | Away Team (Rank) | Away Score | Home Team (Rank) | Home Score | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2021-09-02 | UC-Davis | 19 | Tulsa | 17 | Final | W | 2 |
| 2 | 2021-09-11 | UC-Davis | 53 | San Diego | 7 | Final | W | 46 |
| 3 | 2021-09-18 | Dixie State | 27 | UC-Davis | 60 | Final | W | 33 |
| 4 | 2021-09-25 | UC-Davis | 17 | Weber State | 14 | Final | W | 3 |
| 5 | 2021-10-02 | Idaho | 20 | UC-Davis | 27 | Final | W | 7 |
| 6 | 2021-10-09 | UC-Davis | 17 | Idaho State | 27 | Final | L | -10 |
| 7 | 2021-10-16 | Northern Colorado | 3 | UC-Davis | 32 | Final | W | 29 |
| 8 | 2021-10-23 | UC-Davis | 24 | Cal Poly | 13 | Final | W | 11 |
| 9 | 2021-11-06 | UC-Davis | 40 | Northern Arizona | 24 | Final | W | 16 |
| 10 | 2021-11-13 | Eastern Washington | 38 | UC-Davis | 20 | Final | L | -18 |
| 11 | 2021-11-20 | Sacramento State | 27 | UC-Davis | 7 | Final | L | -20 |
| 12 | 2021-11-27 | UC-Davis (148) | 24 | South Dakota State (126) | 56 | Final | L | -32 |