Schedule:
| Game | Date | Away Team (Rank) | Away Score | Home Team (Rank) | Home Score | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2016-09-03 | Oklahoma Panhandle State | 21 | Sam Houston State | 59 | Final | W | 38 |
| 2 | 2016-09-17 | Sam Houston State | 44 | Lamar | 31 | Final | W | 13 |
| 3 | 2016-09-24 | Sam Houston State | 52 | Houston Baptist | 16 | Final | W | 36 |
| 4 | 2016-10-01 | Stephen F. Austin | 28 | Sam Houston State | 63 | Final | W | 35 |
| 5 | 2016-10-08 | Sam Houston State | 63 | Incarnate Word | 48 | Final | W | 15 |
| 6 | 2016-10-15 | Abilene Christian | 21 | Sam Houston State | 48 | Final | W | 27 |
| 7 | 2016-10-22 | Sam Houston State | 38 | Nicholls State | 21 | Final | W | 17 |
| 8 | 2016-10-29 | Texas Southern | 17 | Sam Houston State | 66 | Final | W | 49 |
| 9 | 2016-11-05 | McNeese State | 43 | Sam Houston State | 56 | Final | W | 13 |
| 10 | 2016-11-12 | Sam Houston State | 48 | Northwestern State | 16 | Final | W | 32 |
| 11 | 2016-11-19 | Central Arkansas | 23 | Sam Houston State | 59 | Final | W | 36 |
| 12 | 2016-12-03 | Chattanooga | 36 | Sam Houston State | 41 | Final | W | 5 |
| 13 | 2016-12-09 | Sam Houston State | 7 | James Madison | 65 | Final | L | -58 |