Schedule:
| Game | Date | Away Team (Rank) | Away Score | Home Team (Rank) | Home Score | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2017-09-02 | Akron (108) | 0 | Penn State (9) | 52 | Final | W | 52 |
| 2 | 2017-09-09 | Pittsburgh | 14 | Penn State | 33 | Final | W | 19 |
| 3 | 2017-09-16 | Georgia State (121) | 0 | Penn State (9) | 56 | Final | W | 56 |
| 4 | 2017-09-23 | Penn State (9) | 21 | Iowa (42) | 19 | Final | W | 2 |
| 5 | 2017-09-30 | Indiana (38) | 14 | Penn State (7) | 45 | Final | W | 31 |
| 6 | 2017-10-07 | Penn State (4) | 31 | Northwestern (91) | 7 | Final | W | 24 |
| 7 | 2017-10-21 | Michigan (15) | 13 | Penn State (3) | 42 | Final | W | 29 |
| 8 | 2017-10-28 | Penn State (2) | 38 | Ohio State (10) | 39 | Final | L | -1 |
| 9 | 2017-11-04 | Penn State (6) | 24 | Michigan State (20) | 27 | Final | L | -3 |
| 10 | 2017-11-11 | Rutgers (78) | 6 | Penn State (8) | 35 | Final | W | 29 |
| 11 | 2017-11-18 | Nebraska (70) | 44 | Penn State (10) | 56 | Final | W | 12 |
| 12 | 2017-11-25 | Penn State (10) | 66 | Maryland (72) | 3 | Final | W | 63 |
| 13 | 2017-12-30 | Washington (11) | 28 | Penn State (8) | 35 | Final | W | 7 |