Schedule:
| Game | Date | Away Team (Rank) | Away Score | Home Team (Rank) | Home Score | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2017-09-02 | Michigan (5) | 33 | Florida (19) | 17 | Final | W | 16 |
| 2 | 2017-09-09 | Cincinnati (104) | 14 | Michigan (5) | 36 | Final | W | 22 |
| 3 | 2017-09-16 | Air Force (44) | 13 | Michigan (5) | 29 | Final | W | 16 |
| 4 | 2017-09-23 | Michigan (5) | 28 | Purdue (114) | 10 | Final | W | 18 |
| 5 | 2017-10-07 | Michigan State (24) | 14 | Michigan (6) | 10 | Final | L | -4 |
| 6 | 2017-10-14 | Michigan (19) | 27 | Indiana (57) | 20 | Final/OT | W | 7 |
| 7 | 2017-10-21 | Michigan (15) | 13 | Penn State (3) | 42 | Final | L | -29 |
| 8 | 2017-10-28 | Rutgers (82) | 14 | Michigan (22) | 35 | Final | W | 21 |
| 9 | 2017-11-04 | Minnesota (70) | 10 | Michigan (22) | 33 | Final | W | 23 |
| 10 | 2017-11-11 | Michigan (22) | 35 | Maryland (67) | 10 | Final | W | 25 |
| 11 | 2017-11-18 | Michigan (19) | 10 | Wisconsin (2) | 24 | Final | L | -14 |
| 12 | 2017-11-25 | Ohio State (8) | 31 | Michigan (20) | 20 | Final | L | -11 |
| 13 | 2018-01-01 | Michigan (27) | 19 | South Carolina (36) | 26 | Final | L | -7 |