Schedule:
| Game | Date | Away Team (Rank) | Away Score | Home Team (Rank) | Home Score | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2017-09-02 | Wyoming (53) | 3 | Iowa (42) | 24 | Final | W | 21 |
| 2 | 2017-09-09 | Iowa (42) | 44 | Iowa State (101) | 41 | Final/OT | W | 3 |
| 3 | 2017-09-16 | North Texas (107) | 14 | Iowa (42) | 31 | Final | W | 17 |
| 4 | 2017-09-23 | Penn State (9) | 21 | Iowa (42) | 19 | Final | L | -2 |
| 5 | 2017-09-30 | Iowa (26) | 10 | Michigan State (40) | 17 | Final | L | -7 |
| 6 | 2017-10-07 | Illinois (76) | 16 | Iowa (35) | 45 | Final | W | 29 |
| 7 | 2017-10-21 | Iowa (20) | 10 | Northwestern (65) | 17 | Final/OT | L | -7 |
| 8 | 2017-10-28 | Minnesota (66) | 10 | Iowa (31) | 17 | Final | W | 7 |
| 9 | 2017-11-04 | Ohio State (5) | 24 | Iowa (26) | 55 | Final | W | 31 |
| 10 | 2017-11-11 | Iowa (20) | 14 | Wisconsin (5) | 38 | Final | L | -24 |
| 11 | 2017-11-18 | Purdue (57) | 24 | Iowa (20) | 15 | Final | L | -9 |
| 12 | 2017-11-24 | Iowa (27) | 56 | Nebraska (74) | 14 | Final | W | 42 |
| 13 | 2017-12-27 | Iowa (24) | 27 | Boston College (31) | 20 | Final | W | 7 |