Schedule:
| Game | Date | Away Team (Rank) | Away Score | Home Team (Rank) | Home Score | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2017-09-02 | Bowling Green (127) | 10 | Michigan State (94) | 35 | Final | W | 25 |
| 2 | 2017-09-09 | Western Michigan | 14 | Michigan State | 28 | Final | W | 14 |
| 3 | 2017-09-23 | Notre Dame (71) | 38 | Michigan State (94) | 18 | Final | L | -20 |
| 4 | 2017-09-30 | Iowa (26) | 10 | Michigan State (40) | 17 | Final | W | 7 |
| 5 | 2017-10-07 | Michigan State (24) | 14 | Michigan (6) | 10 | Final | W | 4 |
| 6 | 2017-10-14 | Michigan State (12) | 30 | Minnesota (51) | 27 | Final | W | 3 |
| 7 | 2017-10-21 | Indiana (54) | 9 | Michigan State (12) | 17 | Final | W | 8 |
| 8 | 2017-10-28 | Michigan State (12) | 31 | Northwestern (44) | 39 | Final/3OT | L | -8 |
| 9 | 2017-11-04 | Penn State (6) | 24 | Michigan State (20) | 27 | Final | W | 3 |
| 10 | 2017-11-11 | Michigan State (14) | 3 | Ohio State (10) | 48 | Final | L | -45 |
| 11 | 2017-11-18 | Maryland (69) | 7 | Michigan State (21) | 17 | Final | W | 10 |
| 12 | 2017-11-25 | Michigan State (18) | 40 | Rutgers (94) | 7 | Final | W | 33 |
| 13 | 2017-12-28 | Washington State | 17 | Michigan State | 42 | Final | W | 25 |