Schedule:
| Game | Date | Away Team (Rank) | Away Score | Home Team (Rank) | Home Score | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2015-09-05 | Illinois State | 14 | Iowa | 31 | Final | L | -17 |
| 2 | 2015-09-12 | Morgan State | 14 | Illinois State | 67 | Final | W | 53 |
| 3 | 2015-09-19 | Illinois State | 34 | Eastern Illinois | 31 | Final/OT | W | 3 |
| 4 | 2015-10-03 | Northern Iowa | 13 | Illinois State | 21 | Final | W | 8 |
| 5 | 2015-10-10 | Illinois State | 31 | Youngstown State | 29 | Final | W | 2 |
| 6 | 2015-10-17 | Illinois State | 38 | Missouri State | 2 | Final | W | 36 |
| 7 | 2015-10-24 | Western Illinois | 28 | Illinois State | 48 | Final | W | 20 |
| 8 | 2015-10-31 | Indiana State | 24 | Illinois State | 27 | Final | W | 3 |
| 9 | 2015-11-07 | Illinois State | 20 | South Dakota State | 25 | Final | L | -5 |
| 10 | 2015-11-14 | Illinois State | 42 | Southern Illinois | 21 | Final | W | 21 |
| 11 | 2015-11-21 | South Dakota | 0 | Illinois State | 46 | Final | W | 46 |
| 12 | 2015-12-05 | Western Illinois | 19 | Illinois State | 36 | Final | W | 17 |
| 13 | 2015-12-11 | Richmond | 39 | Illinois State | 27 | Final | L | -12 |