Schedule:
| Game | Date | Away Team (Rank) | Away Score | Home Team (Rank) | Home Score | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2015-09-05 | South Dakota | 0 | Kansas State | 34 | Final | L | -34 |
| 2 | 2015-09-12 | South Dakota | 27 | UC-Davis | 17 | Final | W | 10 |
| 3 | 2015-09-19 | Drake | 0 | South Dakota | 52 | Final | W | 52 |
| 4 | 2015-10-03 | Youngstown State | 31 | South Dakota | 3 | Final | L | -28 |
| 5 | 2015-10-10 | South Dakota | 21 | Western Illinois | 40 | Final | L | -19 |
| 6 | 2015-10-17 | South Dakota | 24 | North Dakota State | 21 | Final | W | 3 |
| 7 | 2015-10-24 | Missouri State | 10 | South Dakota | 40 | Final | W | 30 |
| 8 | 2015-10-31 | South Dakota | 7 | Northern Iowa | 20 | Final | L | -13 |
| 9 | 2015-11-07 | Southern Illinois | 31 | South Dakota | 34 | Final | W | 3 |
| 10 | 2015-11-14 | South Dakota State | 30 | South Dakota | 23 | Final | L | -7 |
| 11 | 2015-11-21 | South Dakota | 0 | Illinois State | 46 | Final | L | -46 |