Schedule:
| Game | Date | Away Team (Rank) | Away Score | Home Team (Rank) | Home Score | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2016-09-04 | Hampton | 21 | Old Dominion | 54 | Final | L | -33 |
| 2 | 2016-09-10 | William & Mary | 24 | Hampton | 14 | Final | L | -10 |
| 3 | 2016-09-17 | Hampton | 34 | Howard | 7 | Final | W | 27 |
| 4 | 2016-09-29 | Hampton | 9 | North Carolina A&T | 31 | Final | L | -22 |
| 5 | 2016-10-08 | Hampton | 27 | Delaware State | 17 | Final | W | 10 |
| 6 | 2016-10-15 | Morgan State | 12 | Hampton | 21 | Final | W | 9 |
| 7 | 2016-10-22 | Hampton | 14 | Florida A&M | 31 | Final | L | -17 |
| 8 | 2016-10-29 | South Carolina State | 26 | Hampton | 28 | Final | W | 2 |
| 9 | 2016-11-12 | Savannah State (212) | 24 | Hampton (201) | 28 | Final | W | 4 |
| 10 | 2016-11-19 | Norfolk State (241) | 17 | Hampton (198) | 10 | Final | L | -7 |
| 11 | 2016-11-26 | Hampton | 7 | Coastal Carolina | 26 | Final | L | -19 |