Schedule:
Please note: All rankings shown are the rankings of the teams on the date that they played one another
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2016-11-11 | Lehigh (203) | 81 | 84 | Xavier (7) | Final | W | 3 |
| 2 | 2016-11-14 | Buffalo (123) | 53 | 86 | Xavier (7) | Final | W | 33 |
| 3 | 2016-11-17 | Xavier (7) | 83 | 82 | Missouri (164) | Final/OT | W | 1 |
| 4 | 2016-11-18 | Clemson (66) | 77 | 83 | Xavier (7) | Final | W | 6 |
| 5 | 2016-11-20 | Xavier (7) | 67 | 59 | Northern Iowa (82) | Final | W | 8 |
| 6 | 2016-11-26 | Northern Iowa (82) | 42 | 64 | Xavier (7) | Final | W | 22 |
| 7 | 2016-11-29 | North Dakota State (99) | 55 | 85 | Xavier (10) | Final | W | 30 |
| 8 | 2016-12-03 | Xavier (10) | 61 | 76 | Baylor (5) | Final | L | -15 |
| 9 | 2016-12-07 | Xavier (20) | 66 | 68 | Colorado (62) | Final | L | -2 |
| 10 | 2016-12-10 | Utah (69) | 69 | 77 | Xavier (20) | Final | W | 8 |
| 11 | 2016-12-17 | Wake Forest (32) | 65 | 69 | Xavier (27) | Final | W | 4 |
| 12 | 2016-12-20 | Eastern Washington (147) | 56 | 85 | Xavier (23) | Final | W | 29 |
| 13 | 2016-12-28 | Providence (50) | 56 | 82 | Xavier (22) | Final | W | 26 |
| 14 | 2016-12-31 | Xavier (22) | 81 | 76 | Georgetown (60) | Final | W | 5 |
| 15 | 2017-01-07 | St. John's (115) | 82 | 97 | Xavier (16) | Final | W | 15 |
| 16 | 2017-01-10 | Xavier (22) | 54 | 79 | Villanova (3) | Final | L | -25 |
| 17 | 2017-01-14 | Xavier (22) | 78 | 83 | Butler (11) | Final | L | -5 |
| 18 | 2017-01-16 | Creighton (6) | 72 | 67 | Xavier (22) | Final | L | -5 |
| 19 | 2017-01-22 | Georgetown (61) | 75 | 86 | Xavier (25) | Final | W | 11 |
| 20 | 2017-01-26 | Xavier (24) | 78 | 86 | Cincinnati (19) | Final | L | -8 |
| 21 | 2017-01-29 | Xavier (24) | 82 | 77 | St. John's (127) | Final | W | 5 |
| 22 | 2017-02-01 | Seton Hall (50) | 70 | 72 | Xavier (26) | Final | W | 2 |
| 23 | 2017-02-04 | Xavier (26) | 82 | 80 | Creighton (16) | Final | W | 2 |
| 24 | 2017-02-08 | DePaul (174) | 61 | 72 | Xavier (25) | Final | W | 11 |
| 25 | 2017-02-11 | Villanova (2) | 73 | 57 | Xavier (25) | Final | L | -16 |
| 26 | 2017-02-15 | Xavier (24) | 63 | 75 | Providence (57) | Final | L | -12 |
| 27 | 2017-02-18 | Xavier (24) | 61 | 83 | Marquette (46) | Final | L | -22 |
| 28 | 2017-02-22 | Xavier (32) | 64 | 71 | Seton Hall (49) | Final | L | -7 |
| 29 | 2017-02-26 | Butler (21) | 88 | 79 | Xavier (32) | Final | L | -9 |
| 30 | 2017-03-01 | Marquette (40) | 95 | 84 | Xavier | Final | L | -11 |
| 31 | 2017-03-04 | Xavier (38) | 79 | 65 | DePaul (177) | Final | W | 14 |
| 32 | 2017-03-08 | DePaul (177) | 64 | 75 | Xavier (40) | Final | W | 11 |
| 33 | 2017-03-09 | Xavier (40) | 62 | 57 | Butler (19) | Final | W | 5 |
| 34 | 2017-03-10 | Xavier (40) | 72 | 75 | Creighton (24) | Final | L | -3 |
| 35 | 2017-03-16 | Xavier (37) | 76 | 65 | Maryland (29) | Final | W | 11 |
| 36 | 2017-03-18 | Xavier (37) | 91 | 66 | Florida State (12) | Final | W | 25 |
| 37 | 2017-03-23 | Xavier (37) | 73 | 71 | Arizona (7) | Final | W | 2 |
| 38 | 2017-03-25 | Xavier (37) | 59 | 83 | Gonzaga (1) | Final | L | -24 |