Schedule:
Please note: All rankings shown are the rankings of the teams on the date that they played one another
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2016-11-11 | UMKC (275) | 82 | 89 | Creighton (54) | Final | W | 7 |
| 2 | 2016-11-15 | Wisconsin (38) | 67 | 79 | Creighton (54) | Final | W | 12 |
| 3 | 2016-11-18 | Washington State (182) | 77 | 103 | Creighton (54) | Final | W | 26 |
| 4 | 2016-11-20 | North Carolina State (84) | 94 | 112 | Creighton (54) | Final | W | 18 |
| 5 | 2016-11-21 | Ole Miss (83) | 77 | 86 | Creighton (54) | Final | W | 9 |
| 6 | 2016-11-26 | Loyola-Maryland (293) | 52 | 82 | Creighton (54) | Final | W | 30 |
| 7 | 2016-11-29 | Buffalo (172) | 72 | 93 | Creighton (4) | Final | W | 21 |
| 8 | 2016-12-03 | Akron (70) | 70 | 82 | Creighton (4) | Final | W | 12 |
| 9 | 2016-12-07 | Creighton (5) | 77 | 62 | Nebraska (82) | Final | W | 15 |
| 10 | 2016-12-09 | Longwood (343) | 58 | 113 | Creighton (5) | Final | W | 55 |
| 11 | 2016-12-17 | Oral Roberts (322) | 65 | 66 | Creighton (4) | Final | W | 1 |
| 12 | 2016-12-20 | Creighton (5) | 96 | 85 | Arizona State (126) | Final | W | 11 |
| 13 | 2016-12-28 | Seton Hall (43) | 75 | 89 | Creighton (6) | Final | W | 14 |
| 14 | 2016-12-31 | Villanova (1) | 80 | 70 | Creighton (6) | Final | L | -10 |
| 15 | 2017-01-04 | Creighton (6) | 85 | 72 | St. John's (115) | Final | W | 13 |
| 16 | 2017-01-07 | Creighton (6) | 78 | 64 | Providence (62) | Final | W | 14 |
| 17 | 2017-01-11 | Butler (11) | 64 | 75 | Creighton (6) | Final | W | 11 |
| 18 | 2017-01-14 | Truman State | 69 | 101 | Creighton (6) | Final | W | 32 |
| 19 | 2017-01-16 | Creighton (6) | 72 | 67 | Xavier (22) | Final | W | 5 |
| 20 | 2017-01-21 | Marquette (30) | 102 | 94 | Creighton (5) | Final | L | -8 |
| 21 | 2017-01-25 | Creighton (8) | 51 | 71 | Georgetown (71) | Final | L | -20 |
| 22 | 2017-01-28 | DePaul (167) | 66 | 83 | Creighton (8) | Final | W | 17 |
| 23 | 2017-01-31 | Creighton (16) | 76 | 67 | Butler (12) | Final | W | 9 |
| 24 | 2017-02-04 | Xavier (26) | 82 | 80 | Creighton (16) | Final | L | -2 |
| 25 | 2017-02-11 | Creighton (19) | 93 | 58 | DePaul (174) | Final | W | 35 |
| 26 | 2017-02-15 | Creighton (18) | 81 | 87 | Seton Hall (52) | Final | L | -6 |
| 27 | 2017-02-19 | Georgetown (47) | 70 | 87 | Creighton (18) | Final | W | 17 |
| 28 | 2017-02-22 | Providence (54) | 68 | 66 | Creighton (20) | Final | L | -2 |
| 29 | 2017-02-25 | Creighton (20) | 63 | 79 | Villanova (2) | Final | L | -16 |
| 30 | 2017-02-28 | St. John's (98) | 68 | 82 | Creighton (24) | Final | W | 14 |
| 31 | 2017-03-04 | Creighton (24) | 83 | 91 | Marquette (40) | Final | L | -8 |
| 32 | 2017-03-09 | Creighton (24) | 70 | 58 | Providence (43) | Final | W | 12 |
| 33 | 2017-03-10 | Xavier (40) | 72 | 75 | Creighton (24) | Final | W | 3 |
| 34 | 2017-03-11 | Creighton (78) | 60 | 74 | Villanova (29) | Final | L | -14 |
| 35 | 2017-03-17 | Rhode Island (44) | 84 | 72 | Creighton (24) | Final | L | -12 |