Schedule:
Please note: All rankings shown are the rankings of the teams on the date that they played one another
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2016-11-13 | Robert Morris (315) | 72 | 78 | DePaul (170) | Final | W | 6 |
| 2 | 2016-11-17 | Rutgers (273) | 66 | 59 | DePaul (170) | Final | L | -7 |
| 3 | 2016-11-20 | Milwaukee (140) | 59 | 77 | DePaul (170) | Final | W | 18 |
| 4 | 2016-11-23 | Missouri State (208) | 66 | 68 | DePaul (170) | Final | W | 2 |
| 5 | 2016-11-30 | Drake (315) | 75 | 77 | DePaul (84) | Final | W | 2 |
| 6 | 2016-12-03 | DePaul (84) | 64 | 80 | Northwestern (50) | Final | L | -16 |
| 7 | 2016-12-06 | Lamar (251) | 61 | 80 | DePaul (120) | Final | W | 19 |
| 8 | 2016-12-10 | Temple (45) | 74 | 65 | DePaul (120) | Final | L | -9 |
| 9 | 2016-12-14 | Illinois-Chicago (254) | 80 | 75 | DePaul (118) | Final | L | -5 |
| 10 | 2016-12-17 | Chicago State (324) | 61 | 109 | DePaul (118) | Final | W | 48 |
| 11 | 2016-12-19 | Southeast Missouri State (263) | 78 | 81 | DePaul (118) | Final | W | 3 |
| 12 | 2016-12-22 | Wyoming (113) | 72 | 58 | DePaul (133) | Final | L | -14 |
| 13 | 2016-12-23 | Missouri State (115) | 69 | 58 | DePaul (133) | Final | L | -11 |
| 14 | 2016-12-28 | DePaul (149) | 65 | 68 | Villanova (1) | Final | L | -3 |
| 15 | 2017-01-01 | St. John's (153) | 79 | 73 | DePaul | Final | L | -6 |
| 16 | 2017-01-07 | DePaul (157) | 56 | 87 | Seton Hall (38) | Final | L | -31 |
| 17 | 2017-01-10 | Providence (58) | 63 | 64 | DePaul (180) | Final | W | 1 |
| 18 | 2017-01-14 | DePaul (180) | 58 | 83 | Marquette (51) | Final | L | -25 |
| 19 | 2017-01-16 | DePaul (180) | 68 | 78 | St. John's (116) | Final | L | -10 |
| 20 | 2017-01-21 | Butler (17) | 70 | 69 | DePaul (164) | Final/OT | L | -1 |
| 21 | 2017-01-28 | DePaul (167) | 66 | 83 | Creighton (8) | Final | L | -17 |
| 22 | 2017-01-31 | Georgetown (51) | 76 | 73 | DePaul (169) | Final | L | -3 |
| 23 | 2017-02-04 | Marquette (32) | 92 | 79 | DePaul (169) | Final | L | -13 |
| 24 | 2017-02-08 | DePaul (174) | 61 | 72 | Xavier (25) | Final | L | -11 |
| 25 | 2017-02-11 | Creighton (19) | 93 | 58 | DePaul (174) | Final | L | -35 |
| 26 | 2017-02-13 | Villanova (2) | 75 | 62 | DePaul (174) | Final | L | -13 |
| 27 | 2017-02-19 | DePaul (191) | 66 | 82 | Butler (21) | Final | L | -16 |
| 28 | 2017-02-22 | DePaul (189) | 67 | 65 | Georgetown (51) | Final | W | 2 |
| 29 | 2017-02-25 | Seton Hall (49) | 82 | 79 | DePaul (189) | Final | L | -3 |
| 30 | 2017-02-28 | DePaul (177) | 64 | 73 | Providence (44) | Final | L | -9 |
| 31 | 2017-03-04 | Xavier (38) | 79 | 65 | DePaul (177) | Final | L | -14 |
| 32 | 2017-03-08 | DePaul (177) | 64 | 75 | Xavier (40) | Final | L | -11 |