Schedule:
Please note: All rankings shown are the rankings of the teams on the date that they played one another
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2016-11-11 | Lafayette (328) | 48 | 88 | Villanova (1) | Final | W | 40 |
| 2 | 2016-11-14 | Villanova (1) | 79 | 76 | Purdue (13) | Final | W | 3 |
| 3 | 2016-11-17 | Western Michigan (198) | 65 | 76 | Villanova (1) | Final | W | 11 |
| 4 | 2016-11-18 | Villanova (1) | 96 | 77 | Wake Forest (122) | Final | W | 19 |
| 5 | 2016-11-20 | Villanova (1) | 67 | 57 | Central Florida (178) | Final | W | 10 |
| 6 | 2016-11-23 | Charleston (136) | 47 | 63 | Villanova (1) | Final | W | 16 |
| 7 | 2016-11-29 | Villanova (2) | 82 | 57 | Penn (163) | Final | W | 25 |
| 8 | 2016-12-03 | Saint Joseph's (92) | 57 | 88 | Villanova (2) | Final | W | 31 |
| 9 | 2016-12-06 | Villanova (2) | 89 | 79 | La Salle (89) | Final | W | 10 |
| 10 | 2016-12-10 | Notre Dame (7) | 66 | 74 | Villanova (2) | Final | W | 8 |
| 11 | 2016-12-13 | Temple (52) | 57 | 78 | Villanova (1) | Final | W | 21 |
| 12 | 2016-12-21 | American (304) | 48 | 90 | Villanova (1) | Final | W | 42 |
| 13 | 2016-12-28 | DePaul (149) | 65 | 68 | Villanova (1) | Final | W | 3 |
| 14 | 2016-12-31 | Villanova (1) | 80 | 70 | Creighton (6) | Final | W | 10 |
| 15 | 2017-01-04 | Villanova (1) | 58 | 66 | Butler (21) | Final | L | -8 |
| 16 | 2017-01-07 | Marquette (50) | 81 | 93 | Villanova (1) | Final | W | 12 |
| 17 | 2017-01-10 | Xavier (22) | 54 | 79 | Villanova (3) | Final | W | 25 |
| 18 | 2017-01-14 | Villanova (3) | 70 | 57 | St. John's (116) | Final | W | 13 |
| 19 | 2017-01-16 | Seton Hall (36) | 46 | 76 | Villanova (3) | Final | W | 30 |
| 20 | 2017-01-21 | Providence (63) | 68 | 78 | Villanova (2) | Final | W | 10 |
| 21 | 2017-01-24 | Villanova (2) | 72 | 74 | Marquette (33) | Final | L | -2 |
| 22 | 2017-01-29 | Virginia (15) | 59 | 61 | Villanova (2) | Final | W | 2 |
| 23 | 2017-02-01 | Villanova (3) | 66 | 57 | Providence (60) | Final | W | 9 |
| 24 | 2017-02-04 | St. John's (112) | 79 | 92 | Villanova (3) | Final | W | 13 |
| 25 | 2017-02-07 | Georgetown (51) | 64 | 75 | Villanova (2) | Final | W | 11 |
| 26 | 2017-02-11 | Villanova (2) | 73 | 57 | Xavier (25) | Final | W | 16 |
| 27 | 2017-02-13 | Villanova (2) | 75 | 62 | DePaul (174) | Final | W | 13 |
| 28 | 2017-02-18 | Villanova (2) | 92 | 70 | Seton Hall (52) | Final | W | 22 |
| 29 | 2017-02-22 | Butler (21) | 74 | 66 | Villanova (2) | Final | L | -8 |
| 30 | 2017-02-25 | Creighton (20) | 63 | 79 | Villanova (2) | Final | W | 16 |
| 31 | 2017-03-04 | Villanova (2) | 81 | 55 | Georgetown (66) | Final | W | 26 |
| 32 | 2017-03-09 | St. John's (100) | 67 | 108 | Villanova (2) | Final | W | 41 |
| 33 | 2017-03-10 | Seton Hall (41) | 53 | 55 | Villanova (2) | Final | W | 2 |
| 34 | 2017-03-11 | Creighton (78) | 60 | 74 | Villanova (29) | Final | W | 14 |
| 35 | 2017-03-16 | Mount St Mary's (204) | 56 | 76 | Villanova (2) | Final | W | 20 |
| 36 | 2017-03-18 | Wisconsin (23) | 65 | 62 | Villanova (2) | Final | L | -3 |