Schedule:
Please note: All rankings shown are the rankings of the teams on the date that they played one another
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2016-11-11 | McNeese State (334) | 65 | 109 | Purdue (13) | Final | W | 44 |
| 2 | 2016-11-14 | Villanova (1) | 79 | 76 | Purdue (13) | Final | L | -3 |
| 3 | 2016-11-18 | Georgia State (188) | 56 | 64 | Purdue (13) | Final | W | 8 |
| 4 | 2016-11-22 | Purdue (13) | 85 | 64 | Utah State (147) | Final | W | 21 |
| 5 | 2016-11-23 | Purdue (13) | 96 | 71 | Auburn (162) | Final | W | 25 |
| 6 | 2016-11-26 | NJIT (191) | 68 | 79 | Purdue (13) | Final | W | 11 |
| 7 | 2016-11-30 | Purdue (20) | 64 | 71 | Louisville (19) | Final | L | -7 |
| 8 | 2016-12-03 | Morehead State (232) | 56 | 90 | Purdue (20) | Final | W | 34 |
| 9 | 2016-12-06 | Purdue (26) | 97 | 64 | Arizona State (119) | Final | W | 33 |
| 10 | 2016-12-10 | Cleveland State (257) | 53 | 77 | Purdue (26) | Final | W | 24 |
| 11 | 2016-12-17 | Notre Dame (11) | 81 | 86 | Purdue (20) | Final | W | 5 |
| 12 | 2016-12-19 | Western Illinois (340) | 50 | 82 | Purdue (20) | Final | W | 32 |
| 13 | 2016-12-21 | Norfolk State (333) | 45 | 91 | Purdue (16) | Final | W | 46 |
| 14 | 2016-12-28 | Iowa (85) | 67 | 89 | Purdue (15) | Final | W | 22 |
| 15 | 2017-01-01 | Minnesota (16) | 91 | 82 | Purdue | Final/OT | L | -9 |
| 16 | 2017-01-05 | Purdue (17) | 76 | 75 | Ohio State (58) | Final | W | 1 |
| 17 | 2017-01-08 | Wisconsin (22) | 55 | 66 | Purdue (17) | Final | W | 11 |
| 18 | 2017-01-12 | Purdue (14) | 78 | 83 | Iowa (84) | Final | L | -5 |
| 19 | 2017-01-17 | Illinois (51) | 68 | 91 | Purdue (21) | Final | W | 23 |
| 20 | 2017-01-21 | Penn State (66) | 52 | 77 | Purdue (21) | Final | W | 25 |
| 21 | 2017-01-24 | Purdue (17) | 84 | 73 | Michigan State (48) | Final | W | 11 |
| 22 | 2017-01-29 | Purdue (17) | 80 | 83 | Nebraska (86) | Final | L | -3 |
| 23 | 2017-02-01 | Northwestern (25) | 59 | 80 | Purdue (20) | Final | W | 21 |
| 24 | 2017-02-04 | Purdue (20) | 73 | 72 | Maryland (23) | Final | W | 1 |
| 25 | 2017-02-09 | Purdue (16) | 69 | 64 | Indiana (37) | Final | W | 5 |
| 26 | 2017-02-14 | Rutgers (121) | 55 | 74 | Purdue (16) | Final | W | 19 |
| 27 | 2017-02-18 | Michigan State (44) | 63 | 80 | Purdue (16) | Final | W | 17 |
| 28 | 2017-02-21 | Purdue (13) | 74 | 70 | Penn State (72) | Final/OT | W | 4 |
| 29 | 2017-02-25 | Purdue (13) | 70 | 82 | Michigan (35) | Final | L | -12 |
| 30 | 2017-02-28 | Indiana (47) | 75 | 86 | Purdue (15) | Final | W | 11 |
| 31 | 2017-03-05 | Purdue (15) | 69 | 65 | Northwestern (35) | Final | W | 4 |
| 32 | 2017-03-10 | Michigan (30) | 74 | 70 | Purdue (13) | Final/OT | L | -4 |
| 33 | 2017-03-16 | Vermont (57) | 70 | 80 | Purdue (16) | Final | W | 10 |
| 34 | 2017-03-18 | Iowa State (25) | 76 | 80 | Purdue (16) | Final | W | 4 |
| 35 | 2017-03-23 | Purdue (16) | 66 | 98 | Kansas (3) | Final | L | -32 |