Schedule:
Please note: All rankings shown are the rankings of the teams on the date that they played one another
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2015-11-14 | Virginia Military (277) | 50 | 62 | Penn State (80) | Final | W | 12 |
| 2 | 2015-11-17 | DePaul (138) | 62 | 68 | Penn State (80) | Final | W | 6 |
| 3 | 2015-11-20 | Penn State (80) | 52 | 78 | Duquesne (210) | Final | L | -26 |
| 4 | 2015-11-24 | Radford (162) | 86 | 74 | Penn State (80) | Final | L | -12 |
| 5 | 2015-11-28 | Bucknell (176) | 58 | 62 | Penn State (80) | Final | W | 4 |
| 6 | 2015-12-02 | Penn State (80) | 67 | 58 | Boston College (104) | Final | W | 9 |
| 7 | 2015-12-05 | Eastern Michigan (129) | 70 | 81 | Penn State (80) | Final | W | 11 |
| 8 | 2015-12-08 | Penn State (147) | 66 | 76 | George Washington (24) | Final | L | -10 |
| 9 | 2015-12-10 | Canisius (188) | 67 | 81 | Penn State (147) | Final | W | 14 |
| 10 | 2015-12-12 | Louisiana-Monroe (113) | 50 | 54 | Penn State (147) | Final | W | 4 |
| 11 | 2015-12-19 | Penn State (107) | 63 | 57 | Drexel (259) | Final | W | 6 |
| 12 | 2015-12-22 | Penn State (100) | 70 | 71 | Colorado (29) | Final | L | -1 |
| 13 | 2015-12-23 | Penn State (100) | 75 | 69 | Kent State (75) | Final | W | 6 |
| 14 | 2015-12-30 | Penn State (95) | 64 | 70 | Maryland (21) | Final | L | -6 |
| 15 | 2016-01-02 | Penn State (95) | 56 | 79 | Michigan (34) | Final | L | -23 |
| 16 | 2016-01-05 | Minnesota (169) | 77 | 86 | Penn State (115) | Final | W | 9 |
| 17 | 2016-01-10 | Michigan State (2) | 92 | 65 | Penn State (115) | Final | L | -27 |
| 18 | 2016-01-13 | Penn State (119) | 57 | 74 | Purdue (14) | Final | L | -17 |
| 19 | 2016-01-16 | Penn State (119) | 71 | 62 | Northwestern (37) | Final | W | 9 |
| 20 | 2016-01-21 | Wisconsin (77) | 66 | 60 | Penn State (105) | Final | L | -6 |
| 21 | 2016-01-25 | Penn State (105) | 46 | 66 | Ohio State (72) | Final | L | -20 |
| 22 | 2016-01-30 | Michigan (26) | 79 | 72 | Penn State (112) | Final | L | -7 |
| 23 | 2016-02-03 | Penn State (119) | 49 | 73 | Iowa (6) | Final | L | -24 |
| 24 | 2016-02-06 | Indiana (24) | 63 | 68 | Penn State (119) | Final | W | 5 |
| 25 | 2016-02-13 | Penn State (110) | 54 | 70 | Nebraska (96) | Final | L | -16 |
| 26 | 2016-02-17 | Iowa (8) | 75 | 79 | Penn State (122) | Final | W | 4 |
| 27 | 2016-02-20 | Penn State (122) | 70 | 58 | Rutgers (263) | Final | W | 12 |
| 28 | 2016-02-25 | Nebraska (97) | 55 | 56 | Penn State (111) | Final | W | 1 |
| 29 | 2016-02-28 | Penn State (111) | 57 | 88 | Michigan State (5) | Final | L | -31 |
| 30 | 2016-03-03 | Northwestern (72) | 71 | 61 | Penn State (109) | Final | L | -10 |
| 31 | 2016-03-06 | Illinois (118) | 79 | 86 | Penn State (109) | Final/2OT | W | 7 |
| 32 | 2016-03-10 | Penn State (107) | 75 | 79 | Ohio State (61) | Final | L | -4 |